Results 31 to 40 of about 1,328,628 (304)

Late metal-silicate separation on the IAB parent asteroid: Constraints from combined W and Pt isotopes and thermal modelling

, 2018
The short-lived $^{182}$Hf-$^{182}$W decay system is a powerful chronometer for constraining the timing of metal-silicate separation and core formation in planetesimals and planets. Neutron capture effects on W isotopes, however, significantly hamper the
Cook, David L., Ek, Mattias, Golabek, Gregor J., Hunt, Alison C., Lichtenberg, Tim, Reger, Philip M., Schönbächler, Maria   +6 more
core   +1 more source

Body dissatisfaction and low self-esteem in elementary school-aged children: the role of media pressure and trust in parent–child relationships

Frontiers in Psychology
Studies have indicated that the media plays a role in the development of body dissatisfaction in children. Nevertheless, there is limited understanding of the protective factors that may reduce this association, such as the parent–child relationship ...
Jolien De Coen, Sandra Verbeken, Lien Goossens   +2 more
doaj   +1 more source

BRIDGE: A Direct-tree Hybrid N-body Algorithm for Fully Self-consistent Simulations of Star Clusters and their Parent Galaxies [PDF]

, 2007
We developed a new direct-tree hybrid N-body algorithm for fully self-consistent N-body simulations of star clusters in their parent galaxies. In such simulations, star clusters need high accuracy, while galaxies need a fast scheme because of the large ...
Fujii, M., Funato, Y., Iwasawa, M., Makino, J.   +3 more
core   +2 more sources

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Clues to the Origin of Jovian Outer Irregular Satellites from Reflectance Spectra

The Planetary Science Journal
Visible/near-infrared narrowband spectroscopy (dispersion per element ∼ 6 Å) was obtained of the Jovian irregular satellites JVI Himalia, JVII Elara, JVIII Pasiphae, JIX Sinope, JX Lysithea, JXI Carme, JXII Ananke, and JXVII Callirrhoe in 2006, 2009, and
Faith Vilas, Amanda R. Hendrix
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Long-lived magnetism on chondrite parent bodies

Earth and Planetary Science Letters, 2017
Abstract We present evidence for both early- and late-stage magnetic activity on the CV and L/LL parent bodies respectively from chondrules in Vigarano and Bjurbole. Using micro-CT scans to re-orientate chondrules to their in-situ positions, we present a new micron-scale protocol for the paleomagnetic conglomerate test.
Jay Shah, Helena C. Bates, Adrian R. Muxworthy, Dominik C. Hezel, Sara S. Russell, Matthew J. Genge   +5 more
openaire   +4 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Growing Healthy Together: protocol for a randomized clinical trial using parent mentors for early childhood obesity intervention in a Latino community

Trials, 2019
Background Latino children in the US experience high rates of obesity, increasing their risk of subsequent diabetes. There are few clinical trials among low-income, Latino families to test interventions that account for and address their unique situation.
Byron A. Foster, Kelsey Weinstein, Jackilen Shannon   +2 more
doaj   +1 more source