Results 51 to 60 of about 1,328,628 (304)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Compositional characterisation of the Themis family

open access: yes, 2015
Context. It has recently been proposed that the surface composition of icy main-belt asteroids (B-,C-,Cb-,Cg-,P-,and D-types) may be consistent with that of chondritic porous interplanetary dust particles (CPIDPs). Aims.
Binzel, R. P.   +7 more
core   +3 more sources

4. Parent Bodies of Iron Meteorites [PDF]

open access: yesInternational Astronomical Union Colloquium, 1977
On the basis of their chemical and mineralogical composition, 420 iron meteorites have been classified into 12 different groups. Each group seems to have come from a separate parent body. The largest group, IIIAB, probably formed an asteroidal core in a body approximately 100 km in radius, which was largely destroyed by collision 630 My ago. Another 67
openaire   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Iron Oxide Grains in Stardust Track 121 Grains as Evidence of Comet Wild 2 Hydrothermal Alteration [PDF]

open access: yes, 2008
Stardust Track 121 terminal grains contain Fe-oxide.
Bridges, J. C.   +3 more
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Parent–Child Discrepancy on Children’s Body Weight Perception: The Role of Attachment Security

open access: yesFrontiers in Psychology, 2017
The discrepancies between parents and their children on the description of the behavior and representations of their children have been shown in various studies.
Arcangelo Uccula, Gianfranco Nuvoli
doaj   +1 more source

The Tagish Lake chondrite and the interstellar parent body hypothesis [PDF]

open access: yes, 2001
Investigation of the solvent extractable organic compounds in Tagish Lake. The results are used to test the interstellar parent body hypthesis for the origin of extraterrestrial organic ...
Gilmour, I.   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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