Results 91 to 100 of about 1,605,888 (289)

Conflict over condition-dependent sex allocation can lead to mixed sex-determination systems [PDF]

, 2014
Theory suggests that genetic conflicts drive turnovers between sex-determining mechanisms, yet these studies only apply to cases where sex allocation is independent of environment or condition.
Kuijper, B, Pen, Ido, Pen, I, Kuijper, Bram   +3 more
core   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Dynamika vyjednávání o uspořádání péče o děti po rozchodu či rozvodu rodičů

Demografie
Based on data from a questionnaire survey and in-depth qualitative interviews with parents who have separated, the text describes the dynamics of the negotiations relating to physical custody of a child.
Štěpánka Lehmann, Jana Barvíková
doaj   +1 more source

Significance of Healthy Family Structure in Preventing Child Sexual Abuse: A Prospective Controlled Study

Medicine Science, 2014
The aim of this study was to determine the socio-demographic characteristics of victims, parents, and accused or suspected child abusers, and to evaluate the conditions that constitute the risk factors for children falling victim to sexual abuse in ...
Mustafa Talip Sener, Yuksel Anci, Onur Burak Dursun   +2 more
doaj   +1 more source

Post-divorce parental conflict and adolescents' delinquency in divorced families

, 2011
This study reviews several empirical researches which highlight the effect of post-divorce parental conflict as one of the most important factors on adolescents’ delinquency in divorced families. Research consistently shows that parental conflict affects
Yaacob, Siti Nor, Siti Nor Yaacob, Nooshin Sabour, Esmaeili, Nooshin Sabour   +3 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Psychometric Properties of the Multi-Dimensional Co-Parenting After Divorce Questionnaire in the Iranian Population [PDF]

پژوهش‌های علوم شناختی و رفتاری
Given the rising divorce rate in Iran and the critical role of co-parenting quality in children's mental health, a valid instrument to assess this construct is essential.
alireza pezhman, Mahtab Beiranvand, leila Mirahmadi   +2 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Parentification – its direction and perceived benefits in terms of connections with late adolescents’ emotional regulation in the situation of marital conflict

Current Issues in Personality Psychology, 2017
Background Parentification means distortion of the roles between family members. A child performs adult tasks and responsibilities for his siblings and/or parents.
Judyta Borchet, Aleksandra Lewandowska-Walter   +1 more
doaj   +1 more source

Parent-Offspring Conflict [PDF]

American Zoologist, 1974
When parent-offspring relations in sexually reproducing species are viewed from the standpoint of the offspring as well as the parent, conflict is seen to be an expected feature of such relations. In particular, parent and offspring are expected to disagree over how long the period of parental investment should last, over the amount of parental ...
openaire   +1 more source