Results 111 to 120 of about 10,583,601 (308)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Parental effects of Bt toxin and vitamin A on Helicoverpa armigera. [PDF]

PLoS One, 2022
López C, Zanga D, Juárez-Escario A, Muñoz P, Eizaguirre M.   +4 more
europepmc   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Effects of parental acclimation and energy limitation in response to high CO2 exposure in Atlantic cod: survival

, 2018
Effects of parental acclimation and energy limitation in response to high CO2 exposure in Atlantic cod ...
Thorsten B H Reusch (7137947), Christopher R Bridges (8012237), Puvanendran, Velmurugu, Martina H Stiasny (6978350), Bridges, Christopher R, Stiasny, Martina H, Mortensen, Atle, Catriona Clemmesen (6978353), Stig Falk-Petersen (6963116), Gwendolin Göttler (8023577), Atle Mortensen (3072000), Clemmesen, Catriona, Velmurugu Puvanendran (3072006), Falk-Petersen, Stig, Göttler, Gwendolin, Felix H Mittermayer (8016413), Reusch, Thorsten B H, Mittermayer, Felix H   +17 more
core   +1 more source

The relationship between autonomy support from parents and exercise adherence among male Korean adolescents: the multiple mediating effects of resilience and coping style [PDF]

Journal of Men's Health
The purpose of this study was to investigate the effect of parental autonomy support on adolescents’ exercise adherence and the combined mediating effects of psychological resilience and coping style.
Haitao Feng, Jie Guo, Jin Hwang, Zhenhua Shi   +3 more
doaj   +1 more source

Parental effects on offspring sex ratio in the Numbat (Myrmecobius fasciatus): does captivity influence paternal sex allocation? [PDF]

J Mammal, 2023
Firman RC, Ellis CM, Thorn S, Mawson PR.
europepmc   +1 more source

Parental stress in autistic parents: The counseling effects

European Psychiatry, 2017
IntroductionIn parents of autistic children there are high levels of stress. For parents, counseling can help them face the world of autism through the many stressors they experiment.ObjectivesTo evidence a possible effect of the counseling intervention on parental stress.MethodsThe sample consisted of 24 parents (mean age = 38.7) of children diagnosed
Ferrara, R., Esposito, M.
openaire   +2 more sources

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Mitonuclear interactions shape both direct and parental effects of diet on fitness and involve a SNP in mitoribosomal 16s rRNA. [PDF]

PLoS Biol, 2023
Dobson AJ, Voigt S, Kumpitsch L, Langer L, Voigt E, Ibrahim R, Dowling DK, Reinhardt K.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source