Results 51 to 60 of about 834,940 (297)

Sharing & Caring. Division of parental leave from a psychological perspective [PDF]

, 2020
Parents’ preconditions for early parenting vary depending on social and cultural contexts. This thesis provides a psychological perspective on parenting and family life within the context of parental leave in Sweden, framed by Bronfenbrenner’s ...
Lidbeck, Monica
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Fathers’ Experience of Shared Parental Leave in Sweden

Recherches Sociologiques et Anthropologiques, 2007
Since the introduction of the Swedish parental leave reform in 1974, fathers have had the same rights to use parental leave as mothers. Between 2000 and 2003, a research project at the Department of Sociology, University of Gothenburg, focused on fathers
Anders Chronholm
doaj   +1 more source

Social Inclusion or Gender Equality? Political Discourses on Parental Leave in Finland and Sweden

Social Inclusion, 2021
During the 2010s, both Finland and Sweden made advancements in their parental leave systems by widening the right to paid parental leave to a greater diversity of family constellations and investing in gender-equal leave distribution through longer leave
Mikael Nygård, Ann-Zofie Duvander
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Headline prevalence data: national review on discrimination related to pregnancy, parental leave and return to work 2014 [PDF]

, 2014
This survey provides baseline data on discrimination in the workplace related to pregnancy, parental leave and return to work following parental leave.

core  

Fellowship program directors and trainees across the United States find parental leave policies to be inconsistent, inaccessible, and inadequate.

PLoS ONE, 2021
IntroductionDetermine the consistency, accessibility, and adequacy of parental leave policies for adult and pediatric medicine fellowship programs.MethodsWe administered a 40-question survey to fellowship program directors (PDs) and trainees in adult and
Daniel Sabido Jamorabo, Amrin Khander, Vasilios Koulouris, Jeremy Eli Feith, William Matthew Briggs, Benjamin Dwight Renelus   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source