Results 61 to 70 of about 56,746 (296)
SSM: Population Health, 2020 Background: A growing body of research finds that paid leave policies have significant population health benefits for workers and their families, but the lack of a national paid leave policy in the United States leaves most workers without access to any ...
Julia M. Goodman +2 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Fathers’ Experience of Shared Parental Leave in Sweden
Recherches Sociologiques et Anthropologiques, 2007 Since the introduction of the Swedish parental leave reform in 1974, fathers have had the same rights to use parental leave as mothers. Between 2000 and 2003, a research project at the Department of Sociology, University of Gothenburg, focused on fathers
Anders Chronholm
doaj +1 more source
Social Inclusion or Gender Equality? Political Discourses on Parental Leave in Finland and Sweden
Social Inclusion, 2021 During the 2010s, both Finland and Sweden made advancements in their parental leave systems by widening the right to paid parental leave to a greater diversity of family constellations and investing in gender-equal leave distribution through longer leave
Mikael Nygård, Ann-Zofie Duvander
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Headline prevalence data: national review on discrimination related to pregnancy, parental leave and return to work 2014 [PDF]
, 2014 This survey provides baseline data on discrimination in the workplace related to pregnancy, parental leave and return to work following parental leave.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
BMC Pregnancy and ChildbirthBackground The Korean government seeks to balance work and family and alleviate low fertility by implementing a parental leave system. This study aimed to identify the impact of the parental leave system on childbirth among married working women in South
Yun Hwa Jung +2 more
doaj +1 more source