Results 51 to 60 of about 29,368 (292)

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

How Does Parental Mediation Impact Children’s Academic Performance Within the Family System? Evidence from a Nationwide Survey in China

Systems
With the accelerating pace of societal digitalization, parental mediation practices have emerged as a critical mechanism for facilitating children’s socialization within the family system.
Yu Hou, Qunli Tan, Peng Xu
doaj   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Parental Stress and Chinese American Preschoolers’ Adjustment: The Mediating Role of Parenting

Behavioral Sciences, 2023
Family contexts, such as parental stress and parenting practices, play critical roles in preschoolers’ adjustment. However, these processes have been understudied in Chinese American families. The present study examined the associations between Chinese American mothers’ experiences of two types of stress (i.e., general/contextual stress and parenting ...
Suqing Wang, Charissa S. L. Cheah, Xiaoli Zong, Huiguang Ren   +3 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Reducing Harm From Media: A Meta-Analysis of Parental Mediation [PDF]

, 2018
This research investigated the effectiveness of parental mediation on reducing harm from media. Specifically, it examined the magnitude of the effects of three main parental mediation strategies on reducing the amount of media use and the incidence of ...
Liang Chen, Jingyuan Shi
core   +1 more source

Digital play addiction tendency in 5- to 6-year-old children: the role of parental mediation strategies in Russia and Türkiye

Frontiers in Psychology
IntroductionThe rapid digitalization of early childhood has raised growing concerns about the development of digital play addiction among preschoolers.
Olga Almazova, Nesrin Isikoglu, Nebojsa Cokorilo, Patrik Drid, Patrik Drid   +4 more
doaj   +1 more source

Media regulation strategies in parents of 4- to 16-year-old children and adolescents: a cross-sectional study

BMC Public Health, 2023
Background Since children can only control and limit their own media use to a limited extent, it is often the parents who regulate their children’s media use.
Tanja Poulain, Christof Meigen, Wieland Kiess, Mandy Vogel   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source