Results 101 to 110 of about 590,638 (307)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Examining the Correlation between Parental Expectations and Parental Participation: A Meta-Analysis

open access: yesPsikoislamika
Parental expectations play a role in shaping parental involvement, potentially leading to positive outcomes for children. Despite the importance of these factors, research on parental expectations and involvement has been limited in the past two decades.
Novia Solichah   +3 more
doaj   +1 more source

Parental Education and Child’s Education - A Natural Experiment [PDF]

open access: yes
Is the intergenerational educational link due to nature or nurture? In order to answer this dilemma, this paper identifies the effect of parental education on their offspring’s schooling attainment using a discontinuity in the parental educational ...
Arnaud Chevalier
core  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

An Econometric Analysis of Intergenerational Reliance on Social Assistance [PDF]

open access: yes
This paper examines the intergenerational transmission of participation in Québec's social assistance program. The analysis takes into account two sources of intergenerational transmission: one that is due to a causal link between parents' and children's
Beaulieu, Nicolas   +3 more
core  

Ethical Approaches to Adolescent Participation in Sexual Health Research [PDF]

open access: yes, 2007
In this paper we make the case for the importance of adolescent sexual health research, and argue that requiring parental consent for adolescent participation may (a) be unwarranted, (b) be inconsistent with the principles of justice and inclusiveness ...
Adrian Guta, Sarah Flicker
core  

Parental participation and parents' support: effects on mathematics achievement, 2018 national assessment of learning, Mexico. [PDF]

open access: yesFront Psychol, 2023
Hernández-Padilla E   +3 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Child Enjoyment and Parental Satisfaction with Autistic Children’s Participation in Active and Sedentary Activity Configurations

open access: yesDisabilities
This research used proxy reports and questionnaire-based data to explore characteristics related to participation among autistic children. The research aimed to explore child enjoyment and parental satisfaction in different activity configurations ...
Danielle Salters   +2 more
doaj   +1 more source

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