Results 111 to 120 of about 47,869 (219)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Early supplemental parenteral nutrition and risk of subsequent enteroatmospheric fistula in high-risk open abdomen patients with persistent enteral nutrition intolerance: a landmark propensity score-matched cohort study. [PDF]

Front Med (Lausanne)
Wang W, Xie T, Chen C, Chen F, Yang D, Wang P, Li Y.   +6 more
europepmc   +1 more source

Berotralstat and Health‐Related Quality of Life in Hereditary Angioedema: Pooled Analysis of the APeX‐2 and APeX‐J Trials

Clinical &Experimental Allergy, EarlyView.
Pooled analysis of the phase 3 APeX‐2 and APeX‐J trials evaluated the impact of berotralstat 150 mg on health‐related quality of life in patients with hereditary angioedema using the Angioedema Quality of Life (AE‐QoL) questionnaire. Berotralstat significantly improved AE‐QoL total and domain scores for daily functioning and fears/shame versus placebo ...
Teresa Caballero, Sorena Kiani‐Alikhan, Douglas T. Johnston, Aolin Wang, Lorena Lopez‐Gonzalez, Zheng‐Yi Zhou, Fan Yang, Hannah H. Kim, Sandra Nestler‐Parr, Dianne Tomita, Patrick Gillard, Tamar Kinaciyan   +11 more
wiley   +1 more source

Early combined parenteral and enteral nutrition support for patients over 80 years old with non-operative intestinal obstruction. [PDF]

Front Nutr
Chen Z, Zhang P, Liu Y, Xi H.
europepmc   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Identifying a Safety Threshold for Parenteral Glucose Intake in the Early Acute Phase of Preterm Neonates. [PDF]

Nutrients
Di Chiara M, Mastropasqua I, Gloria F, Di Domenico A, Russo F, Dito L, Favata P, Terrin G.   +7 more
europepmc   +1 more source

Prurigo Pigmentosa – an increasingly diagnosed dermatological condition associated with ketogenic diet

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu, Milan Vidakovic, Marcel Krauß, Julia Hyun, Frank Oellig, Thilo Gambichler, Valentina Laura Müller, Alexander Kreuter   +7 more
wiley   +1 more source

De novo activating GUCY2C variant with prenatal bowel dilatation, neonatal functional obstruction, and reversible intestinal failure: A case report. [PDF]

Intest Fail
Cantagalli MM, Amato T, Chioccioli S, Coletta R, Morabito A.   +4 more
europepmc   +1 more source

A retrospective sub‐study of perioperative glycaemia and insulin treatment for hospital inpatients at a quaternary centre from the specialist treatment of inpatients: Caring for diabetes in surgery trial (STOIC‐D Surgery)

Diabetic Medicine, EarlyView.
Abstract Aims Surgical inpatients experience variable glycaemia, with hyper and hypoglycaemia, contributing towards increased morbidity and mortality. Understanding of mechanisms for glycaemic variability and clinician responses remains limited. We aimed to describe patterns of glycaemia in the immediate perioperative period and its drivers, including ...
Florence Ho, Mervyn Kyi, Spiros Fourlanos, Peter G. Colman, Leon J. Worth, Rahul D. Barmanray   +5 more
wiley   +1 more source

The Impact of DRG Payments on Nutritional Therapy Costs for Gastric Cancer Surgery Patients. [PDF]

Healthcare (Basel)
Wu Y, Zhang H, Tang Y, Xie B, Zhang X, Liu M, Cao Q.   +6 more
europepmc   +1 more source