Results 111 to 120 of about 48,013 (266)

Prognostic models for predicting sight‐threatening retinopathy of prematurity in preterm infants: A systematic review

open access: yesActa Ophthalmologica, EarlyView.
Abstract To identify, describe and critically appraise studies developing and/or validating models for predicting sight‐threatening retinopathy of prematurity (ROP) in preterm infants undergoing screening in neonatal intensive care units. PubMed, Embase via Ovid, trial registers, and grey literature were searched from inception to 21 October 2025 ...
Stella Moutzouri   +7 more
wiley   +1 more source

THESS‐ROP study: Development of a prediction model for treatment‐warranted retinopathy of prematurity and external validation of postnatal weight‐gain‐based models in Greece

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To develop THESS‐ROP, a novel prediction model for treatment‐warranted retinopathy of prematurity (TW‐ROP) and compare its performance with four established models in a Greek cohort of consecutively screened preterm infants. Methods This ambispective cohort study included all 526 infants screened for ROP (2016–2022) at the 2nd ...
Stella Moutzouri   +6 more
wiley   +1 more source

Critically Ill Children Show Disrupted Sleep Patterns and Atypical Electroencephalograms: An Observational Cohort Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Sleep disruptions are common in hospitalised children. This study described sleep in critically ill and non‐critically ill hospitalised children, including young infants and patients with central nervous system injuries. Methods This observational cohort study included two groups: critically ill children admitted to a paediatric intensive ...
Eris van Twist   +9 more
wiley   +1 more source

Should Terminal Sedation Be Expanded to Individuals Who Choose to Die Via the Voluntary Stopping of Eating and Drinking?

open access: yesBioethics, EarlyView.
ABSTRACT The voluntary stopping of eating and drinking (VSED) is a phenomenon whereby an individual with decision‐making capacity chooses to cease eating and drinking with the intention of ending their own life. This is widely acknowledged as a lawful, albeit uncommon, end‐of‐life decision.
Laura Gilbertson   +2 more
wiley   +1 more source

Hyperglycaemia as a predictor of morbidity and mortality in patients receiving an allogeneic haematopoietic stem cell transplantation

open access: yesBritish Journal of Haematology, EarlyView.
Summary Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is an effective treatment for patients with haematological malignancies; however, post‐transplant complications, including infections and acute graft‐versus‐host disease (aGvHD), remain significant issues. Identifying modifiable risk factors is therefore critical to improve patient
Marieke Tienstra   +12 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

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