Results 41 to 50 of about 47,869 (219)

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, EarlyView.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source

Severe and Enduring Eating Disorders: A Qualitative Study of Patients' Experiences and Perceived Treatment Needs

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Approximately 25% of individuals with eating disorders develop severe and enduring eating disorders (SEEDs); yet effective treatments remain limited. This study explored lived experiences of SEEDs, focussing on past treatments, as well as current needs and hopes. Method Twenty participants with eating disorders of ≥ 7 years and prior
Emilia Kotilahti, Anu Ruusunen, Katarina Lindstedt, Rasmus Isomaa   +3 more
wiley   +1 more source

Total parenteral nutrition-induced Wernicke’s encephalopathy after oncologic gastrointestinal surgery

Open Medicine, 2020
Carl Wernicke described the disease bearing his name in 1881 and reported three cases characterized by the presence of mental confusion, ataxia, and ophthalmoplegia.
Fedeli Piergiorgio, Justin Davies Richard, Cirocchi Roberto, Popivanov Georgi, Bruzzone Paolo, Giustozzi Michela   +5 more
doaj   +1 more source

Lipid Interference Flagging and Haemoglobin Correction in Lipemic Samples With a Hematology Analyzer

Journal of Clinical Laboratory Analysis, EarlyView.
A flagging method was developed based on the changes of routine blood parameters and blood cell scattergram. It highlights the clinical value of the “Lipid Particles?” flag in effectively identifying lipid interference. This study supports the use of HGB‐O measured by ERP channel as a robust tool for improving diagnostic accuracy in lipid interference ...
Yinhua Fan, Yimin Shen, Dongmei Liu, Yong Wang, Jun Cao, Bo Zhao, Yushuai Ma, Zijie Chen, Shuaishuai Zhang   +8 more
wiley   +1 more source

A case report of a challenging diagnosis of biliary atresia in a patient receiving total parenteral nutrition

BMC Pediatrics, 2019
Background Total parenteral nutrition (TPN) and biliary atresia (BA) are common causes of cholestasis in infancy. The diagnosis of BA is time sensitive due to an inverse correlation between age at intervention (hepatic portoenterostomy - HPE) and ...
Atu Agawu, Andrew Wehrman, Jennifer Pogoriler, Natalie A. Terry, Henry C. Lin   +4 more
doaj   +1 more source

Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition

Case Reports in Neurological Medicine, 2020
Manganese accumulation in the central nervous system creates clinical symptoms of cognitive dysfunction, behavioral changes, and movement disorders resembling Parkinson’s disease.
Alisha Khan, Jonathan Hingre, Amit S. Dhamoon   +2 more
doaj   +1 more source

Low‐value glucose monitoring in noncritically ill hospitalized patients

Journal of Hospital Medicine, EarlyView.
Abstract Background Inpatient routine point‐of‐care glucose (POC‐G) monitoring is common given association of persistent hyperglycemia with increase in morbidity and mortality. However, some patients receive frequent fingerstick testing without needing insulin to reach glycemic targets.
Niloofar Latifi, Nestoras Mathioudakis, Mohammed S. Abusamaan, Megan M. Tschudy, Jianqiao Ma, Sarah Olson, Terra M. M. Jouaneh, Angie Yang, Daniel J. Brotman   +8 more
wiley   +1 more source

Care transition from a pediatric intestinal rehabilitation program to adult care and the risk of all‐cause mortality: A retrospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background As patients with intestinal failure reach adulthood, transitioning to adult care remains challenging because of a lack of specialized programs. This study evaluated outcomes of patients who transitioned care from a pediatric intestinal rehabilitation program.
Gillian R. Goddard, Stephanie Oliveira, Crystal Slaughter, Kim Klotz, Marilyn Stoops, Julie Schletker, Jackie Wessel, Michael Helmrath, Samuel Kocoshis, Monique Goldschmidt, Paul W. Wales   +10 more
wiley   +1 more source

GLIM criteria for the diagnosis of malnutrition in patients with cirrhosis: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This narrative review aims to describe and discuss the validity of the Global Leadership Initiative on Malnutrition (GLIM) criteria in patients with cirrhosis. Methods The literature search was performed in PubMed and EMBASE between May and August 2024 and updated in January 2025, including original studies published in English in ...
Bárbara Chaves Santos, Ana Teresa Limon‐Miro, Puneeta Tandon, Maria Isabel Toulson Davisson Correia, Carla M. Prado, Maria Cristina Gonzalez, Lucilene Rezende Anastácio   +6 more
wiley   +1 more source