Results 31 to 40 of about 71,429 (287)

Stimulation of cholesterol synthesis and hepatic lipogenesis in patients with severe malabsorption

Journal of Lipid Research, 2003
Patients with severe malabsorption have abnormal lipid metabolism with low plasma cholesterol and frequently high triglyceride (TG) levels. The mechanisms behind these abnormalities and the respective roles of malabsorption itself and of the parenteral ...
Ana Cachefo, Philippe Boucher, Eric Dusserre, Paul Bouletreau, Michel Beylot, Cécile Chambrier   +5 more
doaj   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

Production and stability study of a hospital parenteral nutrition solution for neonates

Journal of Pharmaceutical Analysis, 2019
Standard parenteral nutrition solutions are mixtures comprising interacting components that may degrade themselves over time. The objective of this study was to investigate the physicochemical and microbiological stability of a hospital preparation for ...
Anne-Laure Yailian, Céline Serre, Justine Fayard, Marina Faucon, Patrick Thomaré, Samira Filali, Christine Pivot, Florence Vételé, Fabrice Pirot, Emmanuelle Olivier   +9 more
doaj   +1 more source

Bowel Rest with Total Parenteral Nutrition as an Alternative to Diverting Ileostomy in High-Risk Colorectal Anastomosis: A Pilot Study

Medicina, 2022
Anastomotic leakage remains the most feared complication in colorectal surgery. Various intraoperative tests evaluate bowel perfusion and mechanical integrity of the colorectal anastomosis. These tests reduce the risk of postoperative anastomotic leakage;
Marius Kryzauskas, Matas Jakubauskas, Neda Gendvilaite, Vilius Rudaitis, Tomas Poskus   +4 more
doaj   +1 more source

Postoperative Prognostic Nutritional Index as a Useful Prognostic Factor in Patients With Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
In patients after gastric cancer surgery, low postoperative PNI values, considering nutritional status, surgical stress, and postoperative inflammatory response, were significantly associated with poor prognosis in terms of both RFS and OS. ABSTRACT Aim To verify whether postoperative prognostic nutritional index is a useful prognostic factor in ...
Masaaki Yamamoto, Takeshi Omori, Yasunori Masuike, Naoki Shinno, Hisashi Hara, Takahito Sugase, Takashi Kanemura, Atsushi Takeno, Motohiro Hirao, Hiroshi Miyata   +9 more
wiley   +1 more source

Early Enzyme Replacement Therapy Does Not Prevent the Protein Losing Enteropathy Syndrome in Neurovisceral Gaucher Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gaucher disease (GD) is a rare lysosomal storage disorder characterized by multisystemic involvement. With the advent of enzyme replacement therapy (ERT), patient survival has improved, revealing new long‐term complications. We report a case of a 4‐year‐old male with severe neurovisceral GD who developed protein‐losing enteropathy (PLE ...
Vincenza Gragnaniello, Mara Cananzi, Annachiara Cavaliere, Christian Loro, Chiara Cazzorla, Daniela Gueraldi, Andrea Puma, Alberto B. Burlina   +7 more
wiley   +1 more source

Genotype–Phenotype Correlation in TTC7A‐Associated Gastrointestinal Defects and Immunodeficiency Syndrome 1

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gastrointestinal defects and immunodeficiency syndrome 1 (GIDID1) is a rare autosomal recessive disorder caused by biallelic variants in TTC7A. GIDID1 is characterized by a broad clinical spectrum ranging from very early‐onset inflammatory bowel disease (VEOIBD) to multiple intestinal atresia (MIA) with or without immunological manifestations.
Julia Imhoff, Hans Christian Schmidt, Matthias Hans Belau, Johanna Hagens, Mario Lange, Daniel Tegtmeyer, Konrad Reinshagen, Frederike Leonie Harms, Christian Tomuschat   +8 more
wiley   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

La pandemia por COVID-19: hambre, malnutrición y consecuencias sociales para América Latina y el Caribe

Revista de Nutrición Clínica y Metabolismo, 2022
El 11 de marzo de 2020, la Organización Mundial de la Salud anunció que la enfermedad conocida como COVID-19 reunía las condiciones para alcanzar el estatus de pandemia.
Dolores Rodriguez Veintimilla, Luis Marcelo Noles Rodriguez, Evelyn Paola Frias-Toral   +2 more
doaj   +1 more source

Mucoadhesive Polyvinyl Alcohol Film Containing Fridericia chica Extract for Mucositis Treatment: Pharmacological Evaluation and Active Compounds Release

Chemistry &Biodiversity, EarlyView.
ABSTRACT Oral mucositis is a frequent and painful complication of cancer therapy with limited effective options. This study evaluated a mucoadhesive polyvinyl alcohol (PVA) film containing 2.5% Fridericia chica extract as a novel strategy. The formulation was characterized for antioxidant activity, phenolic and flavonoid content, and reactive species ...
Ilza Maria de Oliveira Sousa, Ailane Souza de Freitas, Fabrício de Faveri Favero, Lucia Elaine O. Braga, Mariana Cecchetto Figueiredo, Diana Pinto, Maria Beatriz P. P. Oliveira, Simone Nataly Busato de Feiria, Nubia de Cássia Almeida Queiroz, Ana Lucia T. G. Ruiz, José Francisco Hofling, João Ernesto de Carvalho, Mary Ann Foglio   +12 more
wiley   +1 more source