Results 111 to 120 of about 260,143 (289)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Parenting Skills and Emotional Availability: An RCT

Pediatrics, 2015
OBJECTIVE: To investigate whether a responsive stimulation intervention delivered to caregivers of young children either alone or integrated with nutrition interventions would benefit parenting skills and emotional availability to promote children’s development and growth compared with either a nutrition ...
Yousafzai, Aisha K., Rasheed, Muneera A., Rizvi, Arjumand, Armstrong, Robert, Bhutta, Zulfiqar A.   +4 more
openaire   +3 more sources

Neglect matters: a multi-agency guide for professionals working together on behalf of teenagers [PDF]

, 2010
Neglect matters: a multi-agency guide for professionals working together on behalf of ...
Hicks, Leslie, Stein, Mike
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Parenting Patterns with Science Literacy Skills of Four Grade Elementary School Students

Bisma The Journal of Counseling
Most students still have low interest in science. This can be caused by parenting patterns that are less supportive and motivating. This study aims to analyze the significant relationship between parenting patterns in improving students' scientific ...
Ayu Rusmaladewi, Putu Nanci Riastini, Adrianus I Wayan Ilia Yuda Sukmana   +2 more
doaj   +1 more source

From parenting skills to adolescent treatment needs: Questions elicited by parents of adolescents discharged from residential treatment. [PDF]

Drug Alcohol Depend Rep, 2022
Kelly LM, Correia N, Kearns MDH, Lang SG, Yermash J, Guigayoma J, Helseth SA, Becker SJ.   +7 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

PERAN POLA ASUH ORANG TUA DALAM MEMBANGUN KETERAMPILAN BERPIKIR KRITIS PADA ANAK

Fashluna
Critical thinking is a skill that must be formed from an early age, where children will process and then create a structured series of thoughts from information that they can understand.
Delani Farras Fadhil, Umi Zaroh Barokah, Yusrin Nur Faizah   +2 more
doaj   +1 more source

The Strengths Perspective: Providing Opportunities for Teen Parents and their Families to Succeed [PDF]

, 2016
Majority of teen pregnancy literature and practice is deficit based, focusing on the consequences of teen pregnancy; significantly less research is devoted to the teens’ strengths.
Ricks, Nila
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source