Results 71 to 80 of about 2,848,387 (303)

An evaluation of the Cygnet parenting support programme for parents of children with autism spectrum conditions [PDF]

, 2016
Parents of children on the autistic spectrum often struggle to understand the condition and, related to this, manage their child’s behaviour. Cygnet is a parenting intervention which aims to help parents address these difficulties, consequently improving
Beresford, Bryony Anne, Morris, Andy, Clarke, Susan Evelyn, Beresford, Bryony, Clarke, Susan, Beecham, Jennifer, Stuttard, Lucy   +6 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Exploring mediators of the Amaka Amasanyufu Multiple Family Group Intervention (2016–2022) on parenting stress reduction among caregivers of children with disruptive behavior disorders in Uganda

SSM - Mental Health
Residing in poverty-impacted Ugandan communities and raising children with disruptive behavior disorders (DBDs) is associated with above heightened parenting stress.
Rachel Brathwaite, Massy Mutumba, Fred M. Ssewamala, Ozge Sensoy Bahar, Torsten B. Neilands, Phionah Namatovu, Mary M. McKay, Kimberly Hoagwood   +7 more
doaj   +1 more source

Actor and partner effects of parenting stress and co-parenting on marital conflict among parents of children with atopic dermatitis

BMC Pediatrics, 2020
Background It is important for healthcare providers to pay attention to parents’ rearing style and children’s physical symptoms to promote a healthy quality of life among children with atopic dermatitis.
Jeong Won Han, Hanna Lee
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Parenting stress and affective symptoms in parents of autistic children [PDF]

Science China Life Sciences, 2015
We examined parenting stress and mental health status in parents of autistic children and assessed factors associated with such stress. Participants were parents of 188 autistic children diagnosed with DSM-IV criteria and parents of 144 normally developing children.
Gong, Yun, Du, YaSong, Li, HuiLin, Zhang, XiYan, An, Yu, Wu, Bai-Lin   +5 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

PARENTAL STRESS AMONG AFRICAN AMERICAN PARENTS AND GRANDPARENTS [PDF]

Issues in Mental Health Nursing, 2007
The purpose of this study was to examine the relationships among parental stress, health (defined as level of systolic and diastolic blood pressure and body mass index), childcare characteristics, and social support. The study used a correlational research design and the setting was the metropolitan Detroit area.
Jacquelyn Y, Taylor, Olivia G M, Washington, Nancy T, Artinian, Peter, Lichtenberg   +3 more
openaire   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Parenting self-efficacy mediates relationship between caregiving burden and parenting stress among parents of adolescents with disabilities: a cross-sectional study

Jurnal Ners
Introduction: The study examines the role of parenting self-efficacy as a mediator in the relationship between caregiver burden and parenting stress. Methods: A cross-sectional study was conducted with 204 parents of children with disabilities.
Mundakir Mundakir, Idham Choliq, Sukadiono Sukadiono, Ramadhana Fitriyani Vika, Firman Firman   +4 more
doaj   +1 more source