Results 61 to 70 of about 26,111 (302)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Intergenerational Transmission of Human Parenting Styles to Human–Dog Relationships [PDF]
Parenting style and intergenerational transmission have been extensively studied in parent–child relationships. As dogs are increasingly recognized as integral members of the family system, there is a growing interest in understanding how parenting ...
Sharon Kessler +3 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Frontiers in PsychiatryObjectiveThe purpose of this study is to explore the related risk factors and protective factors of adolescent non suicidal self injury (NSSI).MethodsUtilizing the experience sampling method, we recruited 311 adolescents engaging in NSSI, all without ...
Hong Chen +3 more
doaj +1 more source
Parenting Styles and Parenting Practices in Pediatric Diabetes [PDF]
Diabetes Care, 2011 The influence of parents on both the adherence behavior and the glycemic control of their children and adolescents with diabetes has been documented for several decades. In their article, Shorer et al. (1) focus on the dimension of parental influence that has been defined as “parenting style.” They add to the small but growing literature examining the ...
openaire +2 more sources
Parenting styles, gender roles, and academic burnout among Chinese students: a cultural perspective [PDF]
Academic burnout among Chinese students is particularly severe due to a unique mix of cultural, educational, and family pressures. The strong emphasis placed on academic achievement and high family expectations intensifies this issue.
Wang, Yundi +2 more
core +1 more source
Parenting behavior and the risk of becoming a victim and a bully/victim : a meta-analysis study [PDF]
, 2013 Objective: Being bullied has adverse effects on children's health. Children's family experiences and parenting behavior before entering school help shape their capacity to adapt and cope at school and have an impact on children's peer relationship ...
Samara, Muthanna +3 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Frontiers in PsychologyBackgroundDespite an increasing amount of research on the relationship between parenting styles and neurodevelopmental disorders, there has been minimal focus on how parenting styles impact children’s reading abilities.
Wanyi Wen +14 more
doaj +1 more source