Results 101 to 110 of about 5,810,137 (395)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Suicide is the third cause of death at the age group 10–19 in the world. There are inter multiple risk factors of suicidal behaviours. In the case of children of alcoholics the increased number of suicide attempts is explained by genetic predisposition
Katarzyna Krajewska+2 more
doaj +1 more source
Perceived Stigmatization of Children with Speech-Language Impairment and Their Parents [PDF]
Objective: Developmental disorders in childhood are generally assumed to have stigmatizing effects. The goal of the present study was to assess whether parents of children with speech-language impairment perceive stigmatization of their child or ...
Macharey, Georg+1 more
core +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Communication and support from health-care professionals to families, with dependent children, following the diagnosis of parental life-limiting illness : a systematic review [PDF]
Background: Communication between parents and their children about parental life-limiting illness is stressful. Parents want support from health-care professionals; however, the extent of this support is not known.
Boland, Jason W., Fearnley, Rachel
core +1 more source
Genetic diversity and population structure of the Taigan dog breed
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova+10 more
wiley +1 more source
Recent studies suggest that adolescents are spending significant amounts of time on social media. Brands are taking advantage of this fact and actively using social media to reach adolescent consumers, primarily via social media influencers.
Meng-Hsien Lin+2 more
doaj +1 more source
Parental Perception of Neonates, Parental Stress and Education for NICU Parents
The purpose of this study was to conduct a comparative analysis between the perception of parents with premature infants in the NICU and parents with full-term newborns, and in the process to evaluate the effects of NICU educational support on parents with regard to their perception of neonate and parental stress.A mixed quantitative design was ...
Youngmee Ahn, Namhee Kim
openaire +4 more sources
OBJECTIVE Offspring of parents with severe mental illness (SMI; schizophrenia, bipolar disorder, major depressive disorder) are at an increased risk of developing mental illness.
Daniel Rasic, T. Hajek, M. Alda, R. Uher
semanticscholar +1 more source
Can Parents Create Alcoholics? [PDF]
Background: Research has shown a definitive genetic component to alcoholism, with children of alcoholic parents being much more likely to become alcoholics themselves when compared to children of non-alcoholics.
Boellner, Paul, Lang, Scott
core +1 more source