Results 31 to 40 of about 4,577,115 (316)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Advancing pharmacogenomic research in US Hmong populations: prevalence of key single nucleotide variations in California Hmong

Frontiers in Pharmacology
IntroductionIn collaboration with the Minnesota Hmong community, we have previously discovered significant differences in allele frequencies for key Single Nucleotide Variations (SNVs) within Very Important Pharmacogenes (VIPs) between Hmong and East ...
Boguang Sun, Tou Thao, Kathleen Culhane-Pera, Eric Yang, Mai Yang Thor, Pao Yang, Metta Xiong, Zoua Vang, Robert J. Straka   +8 more
doaj   +1 more source

FUT2 secretor genotype and susceptibility to infections and chronic conditions in the ALSPAC cohort [version 2; referees: 2 approved]

Wellcome Open Research, 2018
Background: The FUT2 (fucosyltransferase-2) gene determines blood group secretor status. Being homozygous for the inactive “non-secretor” rs601338(A) allele confers resistance to certain infections (e.g. Norovirus, Rotavirus) and susceptibility to others
Meghan B. Azad, Kaitlin H. Wade, Nicholas J. Timpson   +2 more
doaj   +1 more source

Parents Online [PDF]

, 2002
Presents findings from surveys conducted between 2000 and 2002. Looks at the use of the Internet and other technology by parents with a child at home, in comparison with non ...
Katherine Allen, Lee Rainie
core  

Parents' future visions for their autistic transition-age youth: hopes and expectations [PDF]

, 2018
Researchers have documented that young adults with autism spectrum disorder have poor outcomes in employment, post-secondary education, social participation, independent living, and community participation. There is a need to further explore contributing
Chen, Jennifer, Cohn, Ellen S., Orsmond, Gael I.   +2 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Parental perceptions of the COVID-19 vaccine for 5- to 11-year-old children: Focus group findings from Worcester Massachusetts

Human Vaccines & Immunotherapeutics, 2022
Vaccine hesitancy is a long-standing public health issue. The present work describes parental perceptions of COVID-19 vaccination for 5- to 11-year-old children, to aid in vaccination efforts.
Melissa Goulding, Grace W. Ryan, Princilla Minkah, Amy Borg, Maricelis Gonzalez, Nelly Medina, Pamela Suprenant, Milagros C. Rosal, Stephenie C. Lemon   +8 more
doaj   +1 more source

Health Savings Account - Eligible High Deductible Health Plans: Updating the Definition of Prevention [PDF]

, 2014
High-deductible health plans (HDHPs) are an important and growing part of the health insurance landscape. By some estimates, as many as 80 percent of large employers may offer an HDHP in 2014.
A. Mark Fendrick, Elizabeth Q. Cliff, Kaden Milkovich, Kathryn Spangler, M. Richard McKellar, Michael Chernew, Stephen Parents   +6 more
core  

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Parenting paradox: Parenting after infant loss

Midwifery, 2011
to gain an in-depth understanding of the parenting experiences of bereaved parents in the years following an infant death.an exploratory qualitative study.semi-structured interview in the participants' homes. Data were collected over a five-month period in 2008 and analysed using thematic analysis.a purposive sample of 13 bereaved parents (10 mothers ...
Warland, J., O'Leary, J., McCutcheon, Helen, Williamson, V.   +3 more
openaire   +5 more sources