Results 31 to 40 of about 3,203 (180)

Enhanced renoprotective actions of Paricalcitol and omega-3 fatty acids co-therapy against diabetic nephropathy in rat

Journal of Advanced Research, 2022
Introduction: Although the synthetic vitamin D analogue, Paricalcitol, and omega-3 Fatty acids (ω-3) alleviated diabetic nephropathy (DN), their combination was not previously explored.
Mohamed El-Boshy, Aiman Alsaegh, Ahmed H. Qasem, Ramya A. Sindi, Abdelghany H. Abdelghany, Hossam Gadalla, Doha Reda, Firas Azzeh, Shakir Idris, Jawwad Ahmad, Bassem Refaat, PhD   +10 more
doaj   +1 more source

Paricalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E₂ Receptor EP4 Pathway [PDF]

, 2017
The protective mechanism of paricalcitol remains unclear in renal ischemia-reperfusion (IR) injury. We investigated the renoprotective effects of paricalcitol in IR injury through the prostaglandin E2 (PGE2) receptor EP4.
Yu Ah Hong, Hyunsu Choi, Ki Cheol Park, Suk Young Kim, Keum Jin Yang, Jeong Min Oh, Sang Ju Lee, Cheol Whee Park, Yoon Kyung Chang, Chul Woo Yang, Hyeon Seok Hwang, So Young Jung   +11 more
core   +1 more source

Three Therapeutic Strategies: Cinacalcet, Paricalcitol or Both in Secondary Hyperparathyroidism Treatment in Hemodialysed Patients During 1-Year Observational Study—A Comparison

Frontiers in Endocrinology, 2019
Introduction: Secondary hyperparathyroidism (sHPT) is a common hormonal complication of chronic kidney disease. There are several therapeutic options for sHPT management aiming at calcium-phosphorus balance normalization and decrease of parathormone ...
Jacek Zawierucha, Jolanta Malyszko, Jacek S. Malyszko, Tomasz Prystacki, Wojciech P. Marcinkowski, Teresa Dryl-Rydzynska   +5 more
doaj   +1 more source

Effect of paricalcitol vs calcitriol on hemoglobin levels in chronic kidney disease patients: a randomized trial. [PDF]

PLoS ONE, 2015
Recent studies suggest that vitamin D deficiency represents an additional cofactor of renal anemia, with several mechanisms accounting for this relationship.
Eleonora Riccio, Massimo Sabbatini, Dario Bruzzese, Ivana Capuano, Silvia Migliaccio, Michele Andreucci, Antonio Pisani   +6 more
doaj   +1 more source

Antioxidant and renoprotective effects of paricalcitol on experimental contrast-induced nephropathy model

, 2012
Objectives: The aim of the study was to assess the effect of paricalcitol on the experimental contrast-induced nephropathy (CIN) model. We hypothesised that paricalcitol may prevent CIN.
ÖZEN ALAHDAB, YEŞİM
core   +2 more sources

Efecto regulador de paricalcitol sobre parámetros inflamatorios, fibróticos y anticalcificantes en el paciente con enfermedad renal crónica. Más allá de la regulación de la enfermedad óseo-mineral

Nefrología, 2020
Resumen: Antecedentes: La principal causa de morbimortalidad en el paciente con enfermedad renal crónica (ERC) es la cardiovascular. La inflamación y las alteraciones en el metabolismo óseo-mineral en estos pacientes conllevan aumento del riesgo ...
Laura Salanova Villanueva, Yohana Gil Giraldo, Begoña Santos Sánchez-Rey, Abelardo Aguilera Peralta   +3 more
doaj   +1 more source

Combination Therapy with Enalapril and Paricalcitol Ameliorates Streptozotocin Diabetes-Induced Testicular Dysfunction in Rats via Mitigation of Inflammation, Apoptosis, and Oxidative Stress

Pathophysiology, 2023
Background: As the impacts of diabetes-induced reproductive damage are now evident in young people, we are now in urgent need to devise new ways to protect and enhance the reproductive health of diabetic people.
Magdy Y. Elsaeed, Osama Mahmoud Mehanna, Ezz-Eldin E. Abd-Allah, Mohamed Gaber Hassan, Walid Mostafa Said Ahmed, Abd El Ghany A. Moustafa, Gaber E. Eldesoky, Amal M. Hammad, Usama Bahgat Elgazzar, Mohamed R. Elnady, Fatma M. Abd-Allah, Walaa M. Shipl, Amr Mohamed Younes, Mostafa Rizk Magar, Ahmed E. Amer, Mohamed Ali Mahmoud Abbas, Khaled Saleh Ali Elhamaky, Mohammed Hussien Mohammed Hassan   +17 more
doaj   +1 more source

Paricalcitol Protects Peritoneal Membrane Function in Encapsulating

, 2016
OBJECTIVE: The most lethal complication of peritoneal dialysis is encapsulating peritoneal sclerosis (EPS), which develops as a result of epithelio-mesenchymal transformation (EMT) and known fibrotic processes.
Yıldız, Abdülmecit, Güllülü, Mustafa, Yavuz, Mahmut, Berna Vuruşkan, Gül, Özen Öz, Özen Öz Gül, Ayşegül Oruç, Aktaş, Nimet, Cuma Bülent Gül, Dilek, Kamil, Abdulmecit Yıldız, Mahmut Yavuz, Mustafa Güllülü, Nimet Aktaş, Alparslan Ersoy, Kamil Dilek, Yurtkuran, Mustafa Abbas, Gül, Cuma Bülent, Mustafa Abbas Yurtkuran, Vuruşkan, Berna, Oruç, Ayşegül, Ersoy, Alparslan   +21 more
core   +1 more source

Paricalcitol versus Calcitriol + Cinacalcet for the Treatment of Secondary Hyperparathyroidism in Chronic Kidney Disease in China: A Cost-Effectiveness Analysis

Frontiers in Public Health, 2021
Background: Chronic Kidney Disease (CKD) is a global chronic disease with increasing prevalence in recent years, particularly CKD accompanied by Secondary Hyperparathyroidism (SHPT) leads to reduced quality of life, increased mortality, a considerable ...
Zhuolin Zhang, Lele Cai, Hong Wu, Hong Wu, Xinglu Xu, Wenqing Fang, Xuan He, Xiao Wang, Xin Li, Xin Li, Xin Li   +10 more
doaj   +1 more source

Effects of calcitriol and paricalcitol on renal fibrosis in CKD

Nephrology Dialysis Transplantation, 2021
Abstract Background In chronic kidney disease, the activation of the renin–angiotensin–aldosterone system (RAAS) and renal inflammation stimulates renal fibrosis and the progression to end-stage renal disease.
Laura Martínez-Arias, Sara Panizo, Cristina Alonso-Montes, Julia Martín-Vírgala, Beatriz Martín-Carro, Sara Fernández-Villabrille, Carmen García Gil-Albert, Carmen Palomo-Antequera, José Luis Fernández-Martín, María Piedad Ruiz-Torres, Adriana S Dusso, Natalia Carrillo-López, Jorge B Cannata-Andía, Manuel Naves-Díaz   +13 more
openaire   +4 more sources