Results 51 to 60 of about 3,203 (180)

Paricalcitol protects against hydrogen peroxide-induced injury in endothelial cells through suppression of apoptosis

open access: yes, 2022
The vascular endothelium is one of the main targets of oxidative stress which plays an important role in the pathophysiology of vascular damage. Recent studies show that vitamin D can positively regulate endothelial functions in various chronic diseases ...
ŞEKERLER, TURGUT, ŞENER, AZİZE
core   +1 more source

Paricalcitol changed the peritoneal T cell population in mice instilled with PDF.

open access: yes, 2014
A) The paricalcitol group tends to increase the number of nucleated cells at the peritoneal cavity compared with the PDF group. B) The number of B cells was similar in the PDF and paricalcitol groups.
Teresa Bellón (3929789)   +7 more
core   +1 more source

Paricalcitol regulatory effect on inflammatory, fibrotic and anticalcificating parameters in renal patient. Far beyond mineral bone disease regulation

open access: yesNefrología (English Edition), 2020
Backward: Cardiovascular events are the major cause of morbidity and mortality in patients with chronic kidney disease (CKD). Inflammation and mineral-bone disorder are pathological conditions that have been associated with an increased cardiovascular ...
Laura Salanova Villanueva   +3 more
doaj   +1 more source

Comparison of the Pharmacological Effects of Paricalcitol and Doxercalciferol on the Factors Involved in Mineral Homeostasis

open access: yesInternational Journal of Endocrinology, 2010
Vitamin D receptor agonists (VDRAs) directly suppress parathyroid hormone (PTH) mRNA expression. Different VDRAs are known to have differential effects on serum calcium (Ca), which may also affect serum PTH levels since serum Ca regulates PTH secretion ...
J. Ruth Wu-Wong   +4 more
doaj   +1 more source

Effects of oral paricalcitol therapy on arterial stiffness and osteopontin in hypertensive patients with chronic kidney disease and secondary hyperparathyroidism

open access: yesHellenic Journal of Cardiology, 2019
Background: Arterial stiffness is linked to the progression of atherosclerosis, while activation of vitamin D receptor exerts favorable cardiovascular effects in patients with renal insufficiency.
Michalis Giakoumis   +10 more
doaj   +1 more source

Paricalcitol and Peritoneal Protein Loss in Peritoneal Dialysis: A Double-Center Study

open access: yes, 2018
<b><i>Background/Aims:</i></b> Peritoneal protein loss (PPL) is associated with cardiovascular disease and mortality in peritoneal dialysis (PD).
Anabela Malho Guedes   +6 more
core   +1 more source

Vitamin D Receptor Activation Mitigates the Impact of Uremia on Endothelial Function in the 5/6 Nephrectomized Rats

open access: yesInternational Journal of Endocrinology, 2010
Endothelial dysfunction increases cardiovascular disease risk in chronic kidney disease (CKD). This study investigates whether VDR activation affects endothelial function in CKD.
J. Ruth Wu-Wong   +6 more
doaj   +1 more source

Long-Term Therapy with Paricalcitol for Secondary Hyperparathyroidism in Hemodialysis Patients

open access: yes, 2003
Purpose The efficacy of the vitamin D analog paricalcitol has mainly been shown in short-term studies. There are limited data regarding long-term treatment with this agent.
S. Lin   +3 more
core   +1 more source

Effects of Paricalcitol and Enalapril on Atherosclerotic Injury in Mouse Aortas

open access: yes, 2010
<i>Aims:</i> This study investigated the protective effect of vitamin D analog paricalcitol combined with angiotensin-converting enzyme inhibitor (enalapril) on aortic oxidative injury in atherosclerotic mice.
Kazim Husain   +3 more
core   +1 more source

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