Evaluation of Therapeutic Potentials of α-Lipoic Acid Versus Stem Cells-Derived Microvesicles Against Experimentally–Induced Gastric Ulcer in Adult Male Albino Rats (Light and Electron microscopic study) [PDF]
Background: Alpha-Lipoic acid (ALA), is an antioxidant endogenous substance. It is available in small amounts in food. Mesenchymal stem cells (MSCs) derived microvesicles (MSC-MVs) have numerous paracrine protective effects against tissue injury that are
Sherifa Abd El-Salam +2 more
doaj +1 more source
Context Hydrogen sulphide (H2S) has been proved to be a neuromodulator and contributes to the maintenance of gastric mucosal integrity in damage caused by anti-inflammatory nonsteroidal drugs.
Jand-Venes Rolim MEDEIROS +3 more
doaj +1 more source
Parietal cell distribution informs gastric bypass procedure [PDF]
INTRODUCTION: Roux-en-Y Gastric Bypass (RYGB) is a common bariatric procedure that facilitates weight loss and reduces co-morbidities of obesity. A common complication is marginal ulceration, caused by an overproduction of hydrochloric acid from the ...
Rukavina, Nadia A.
core +1 more source
dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins
Double‐stranded RNA (dsRNA) plays an important role in the innate immune system, but can be misregulated in disease, leading to inflammation. Despite the importance of this motif, methods for detecting dsRNA remain limited. This work shows that ADAR3 can be repurposed to provide improved detection of dsRNA, which is demonstrated in the context of viral
Weina Cheng +7 more
wiley +2 more sources
Helicobacter suis affects the health and function of porcine gastric parietal cells [PDF]
The stomach of pigs at slaughter age is often colonized by Helicobacter (H.) suis, which is also the most prevalent gastric non-H. pylori Helicobacter (NHPH) species in humans. It is associated with chronic gastritis, gastric ulceration and other gastric
Ducatelle, Richard +11 more
core +1 more source
17Beta-estradiol modulates gastroduodenal preneoplastic alterations in rats exposed to the carcinogen N-methyl-N'-nitro-nitrosoguanidine [PDF]
Gastric cancers are a significant cause of morbidity worldwide. Epidemiological studies and animal models show that males have higher incidences of gastric cancers compared with females, suggesting that sex hormones may modulate gastric cancer risk.
Reyher, K K +4 more
core +1 more source
Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
Ivana Hitkova (401838) +37 more
core +2 more sources
Do we need gastric acid? [PDF]
Evidence from comparative anatomy and physiology studies indicates that gastric acid secretion developed during the evolution of vertebrates approximately 350 million years ago.
Lippl, F. +27 more
core +1 more source
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Human cell line (HGC-27) derived from the metastatic lymph node of gastric cancer [PDF]
A cell line (HGC-27) was established by culture of the metastatic lymph node from a gastric cancer patient diagnosed histologically as undifferentiated carcinoma.
Kimoto, Tetsuo, Akagi, Tadaatsu
core +1 more source

