Results 251 to 260 of about 6,468,123 (361)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Safe, Simple, and Rapid: A Minimally Invasive Coding Technique for Identifying Individuals of the Endangered Mongolian Racerunner (<i>Eremias argus</i>). [PDF]

Ecol Evol
Song JY, Chang MH, Kim SB, Koo KS.
europepmc   +1 more source

Design Aspects Applied to Engineering: Technology Sustainable Development and Innovation in the Science Parks

, 2016
Ekaterina Emmanuil Inglesis Barcellos, Galdenoro Botura, Luís Carlos Paschoarelli   +2 more
openalex   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Orchard Park Central School District and Orchard Park Principals Association (2003) [PDF]

, 2003

core   +1 more source

Evaluation of the private participation in the implementation and management of ecotourism in cavernas do Peruaçu national park, Brazil

, 2019
Hugo Rodrigues Araujo, Heros Augusto Santos Lobo, Luiz Eduardo Panisset Travassos   +2 more
openalex   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Human carnivore conflict in and around Borena Sayint Worehimanu National Park, South Wollo, Amhara Region, Ethiopia: A community-based cross-sectional study design. [PDF]

BMC Zool
Abdu I, Seid Muhie N.
europepmc   +1 more source

Hyde Park Central School District and Hyde Park Administrators Association (2002) [PDF]

, 2002

core   +1 more source