Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
<i>Synergus nigrus</i> (Hymenoptera, Cynipidae, Synergini), a new inquiline species reared from galls of <i>Philonix nigra</i> Gillette, 1889 (Cynipidae, Cynipini). [PDF]
Montelongo DC +3 more
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New Hyde Park-Garden City Park Union Free School District and New Hyde Park-Garden City Park Clerical Unit, CSEA, AFSCME, AFL-CIO, Local 1000 & 830 (1997) [PDF]
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
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Island Park Union Free School District and Island Park Faculty Association (2014) (MOA) [PDF]
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Bleeding Risk Is Not Increased When Initiating Therapeutic Plasma Exchange in Adults Using Exclusively Albumin Replacement Fluid 2 Days After Percutaneous Kidney Biopsy. [PDF]
Raval JS, Rollins-Raval MA, Park YA.
europepmc +1 more source
Island Park Union Free School District and Island Park Administrators Association (2005) [PDF]
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

