Results 11 to 20 of about 322,606 (360)
The Lancet, 2021 Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; the rising prevalence worldwide resembles the many characteristics typically observed during a pandemic, except for an infectious cause.
Bloem, B.R., Okun, M.S., Klein, C.
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Progress Notes : a report from the Parkinson's Disease Center at Boston University Medical Center [PDF]
, 1991 News and updates from the Boston University Medical Center Parkinson's Disease ...
Parkinson's Disease Center at Boston University Medical Center
core +11 more sources
Frontiers in Neurology, 2022 Background: Fatigue is a common symptom in patients with Multiple system atrophy (MSA), but effective treatments remain elusive. The present study aims to investigate whether high-frequency repetitive transcranial magnetic stimulation (rTMS) over the ...
Jing Pan +10 more
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The Lancet, 2004 Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals.
Samii, Ali +2 more
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Familial Parkinson’s Disease/Parkinsonism [PDF]
BioMed Research International, 2015 Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by parkinsonism (bradykinesia, resting tremor, rigidity, and postural instability) with good response to L-dopa. Although the majority of PD patients are sporadic, it is now clear that genetic factors contribute to the pathogenesis of PD.
Hiroyuki Tomiyama +3 more
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Case Report: Progressive Asymmetric Parkinsonism Secondary to CADASIL Without Dementia
Frontiers in Neurology, 2022 Parkinsonism is a rare phenotype of cerebral autosomal dominant arteriopathy with subcortical infarction and leukoencephalopathy (CADASIL), all of which involve cognitive decline. Normal cognition has not been reported in previous disease studies.
Weihang Guo +23 more
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Annals of Indian Academy of Neurology, 2011 These guidelines present evidence for interventions to manage early stage, uncomplicated Parkinson's Disease. This includes pharmacological and non-pharmacological interventions. The evidence for pharmacological agents to provide neuroprotection or disease modification, such as a delay in disease progression, is discussed, with no trials demonstrating ...
Behari, Madhuri +11 more
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Stability of MDS-UPDRS Motor Subtypes Over Three Years in Early Parkinson's Disease
Frontiers in Neurology, 2021 Background: Various classifications have been proposed to subtype Parkinson's disease (PD) based on their motor phenotypes. However, the stability of these subtypes has not been properly evaluated.Objective: The goal of this study was to understand the ...
Abhijeet K. Kohat +33 more
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Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice.
Frontiers in Cellular Neuroscience, 2013 Striatal functions depend on the activity balance between the dopamine and glutamate neurotransmissions. Glutamate inputs activate cyclin-dependent kinase 5 (Cdk5), which inhibits postsynaptic dopamine signaling by phosphorylating DARPP-32 (dopamine- and
Yukio eYamamura +9 more
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Aberrant functional connectivity within the basal ganglia of patients with Parkinson's disease
NeuroImage: Clinical, 2015 Resting state functional MRI (rs-fMRI) has been previously shown to be a promising tool for the assessment of early Parkinson's disease (PD). In order to assess whether changes within the basal ganglia network (BGN) are disease specific or relate to ...
Michal Rolinski +8 more
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