Results 41 to 50 of about 214,205 (284)

Optimal set of EEG features for emotional state classification and trajectory visualization in Parkinson's disease [PDF]

, 2014
In addition to classic motor signs and symptoms, individuals with Parkinson's disease (PD) are characterized by emotional deficits. Ongoing brain activity can be recorded by electroencephalograph (EEG) to discover the links between emotional states and ...
Mohamad, Khairiyah, Yuvaraj, Rajamanickam, Ibrahim, Norlinah Mohamed, Omar, Mohd Iqbal, Murugappan, Murugappan, Sundaraj, Kenneth, Palaniappan, Ramaswamy   +6 more
core   +1 more source

Everyday walking with Parkinson's disease: understanding personal challenges and strategies

, 2008
PURPOSE: This qualitative study was designed to explore the personal experience of everyday walking with Parkinson's disease (PD), the challenges and the strategies employed to compensate for difficulties, to help contextualise the scientific knowledge ...
Nieuwboer, Alice, Hetherington, V., Willems, A.M., van Wegen, E.E.H., Kwakkel, Gert, Rochester, Lynn, Jones, Diana, Birleson, A., Rochester, L., Jones, D.A., van Wegen, Erwin, Birleson, Angela, Nieuwboer, A., Hetherington, Victoria, Willems, Anne-Marie, Kwakkel, G.   +15 more
core   +1 more source

Relationship between Fatigue and Nocturnal Problems Related to Parkinson's Disease [PDF]

, 2022
In patients with Parkinson's disease (PD), fatigue and sleep disturbances are important non-motor symptoms. In this study, we aimed to evaluate the relationship between fatigue and sleep disturbances in patients with Parkinson's disease (PD).
Nozawa, Narihiro, Shioda, Mukuto, Sakuramoto, Hirotaka, Suzuki, Keisuke, Onuma, Hiroki, Fujita, Hiroaki, Shiina, Tomohiko, Ogaki, Keitaro   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Emotion classification in Parkinson's disease by higher-order spectra and power spectrum features using EEG signals: A comparative study [PDF]

, 2014
Deficits in the ability to process emotions characterize several neuropsychiatric disorders and are traits of Parkinson's disease (PD), and there is need for a method of quantifying emotion, which is currently performed by clinical diagnosis ...
Mohamad, Khairiyah, Yuvaraj, Rajamanickam, Ibrahim, Norlinah Mohamed, Omar, Mohd Iqbal, Murugappan, Murugappan, Sundaraj, Kenneth, Satiyan, Marimuthu, Palaniappan, Ramaswamy   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Applications of the European Parkinson's Disease Association sponsored Parkinson's Disease Composite Scale (PDCS).

, 2019
This study was addressed to determine the presence of Parkinson disease (PD) manifestations, their distribution according to motor subtypes, and the relationships with health-related quality of life (QoL) using the recently validated European Parkinson's
Rodriguez-Blazquez C, Martinez-Martin P, Hurtado González, Carlos Alberto, Chaudhuri KR, Radicati FG, PDCS European Study Group, Stocchi F, Balestrino R   +7 more
core   +2 more sources

There Is No Parkinson Disease [PDF]

Archives of Neurology, 2008
The term Parkinson disease defines a specific clinical condition characterized by a typical history and characteristic signs. This review examines the historical evolution of the concept of Parkinson disease and how the misunderstanding of Parkinson disease may be hindering clinical research trials. It is proposed that this syndrome be called Parkinson
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The frequency and validity of self-reported diagnosis of Parkinson's Disease in the UK elderly: MRC CFAS cohort

, 2006
Background: Estimates of the incidence and prevalence of chronic diseases can be made using established cohort studies but these estimates may have lower reliability if based purely on self-reported diagnosis.Methods: The MRC Cognitive Function & Ageing ...
MRC CFAS, The, Matthews, FE, Foltynie, Thomas, Brayne, C, Carol Brayne, Thomas Foltynie, Ishihara, Lianna, null null, Brayne, Carol, Lianna Ishihara, Foltynie, T, Ishihara, L, Matthews, Fiona E., Fiona E Matthews   +13 more
core   +1 more source