Results 21 to 30 of about 150,438 (100)

Severe Constipation in Parkinson's Disease and in Parkinsonisms: Prevalence and Affecting Factors

Frontiers in Neurology, 2019
Background: constipation is one of the most common and disabling non-motor symptoms of Parkinson Disease (PD) and Parkinsonisms (PS). Few studies evaluate the difference of prevalence between PD and PS and the cause leading to a severe constipation in ...
Giuseppe Frazzitta, Davide Ferrazzoli, Annarita Folini, Grazia Palamara, Roberto Maestri   +4 more
doaj   +1 more source

Dopamine agonists in Parkinson’s disease: Impact of D1-like or D2-like dopamine receptor subtype selectivity and avenues for future treatment

Clinical Parkinsonism & Related Disorders, 2023
Dopamine agonists (DAs) have demonstrated efficacy for the treatment of Parkinson’s disease (PD) but are limited by adverse effects (AEs). DAs can vary considerably in their receptor subtype selectivity and affinity, chemical composition, receptor ...
Stuart H. Isaacson, Robert A. Hauser, Rajesh Pahwa, David Gray, Sridhar Duvvuri   +4 more
doaj   +1 more source

Understanding health care needs among Veterans with Parkinson's disease: A survey study

Frontiers in Neurology, 2022
Among Veterans, it is estimated that 110,000 are living with Parkinson's disease (PD) in the United States. Whether or not Veterans living with PD are enrolled in the Veterans Health Administration (VHA), they may require special considerations when it ...
Megan Feeney, John Duda, Amie Hiller, Amie Hiller, Jay Phillips, Christiana Evers, Nicole Yarab, Veronica Todaro, Lydia Rader, Sheera Rosenfeld   +9 more
doaj   +1 more source

Mild Cognitive Impairment in Parkinson’s Disease: A Review of Current Concepts

Neurology Research International, 2013
Mild Cognitive Impairment in Parkinson’s Disease (PD-MCI) is common and may be associated with accelerated progression to dementia. Considering the importance of this emerging entity, new diagnostic criteria have recently been proposed. Early recognition
Natalie C. Palavra, Sharon L. Naismith, Simon J. G. Lewis   +2 more
doaj   +1 more source

Treatment of dystonia and tics

Clinical Parkinsonism & Related Disorders, 2020
Treatment of dystonia and tics continues to evolve. In dystonia, while oral agents such as benzodiazepines, baclofen and anticholinergics remain in use, botulinum toxin (BoNT) continues to be regarded as the treatment of choice for focal and segmental ...
Steven Bellows, Joseph Jankovic
doaj   +1 more source

Physical Activity Improves Anxiety and Apathy in Early Parkinson's Disease: A Longitudinal Follow-Up Study

Frontiers in Neurology, 2021
Objective: In a prospective study, we investigated the association between physical activity and various motor, non-motor outcomes, and quality of life in early Parkinson's disease (PD) participants in the PD Longitudinal Singapore Study.Background ...
Samuel Yong-Ern Ng, Samuel Yong-Ern Ng, Nicole Shuang-Yu Chia, Nicole Shuang-Yu Chia, Mirza Masoom Abbas, Mirza Masoom Abbas, Ehsan Seyed Saffari, Xinyi Choi, Xinyi Choi, Dede Liana Heng, Dede Liana Heng, Zheyu Xu, Zheyu Xu, Zheyu Xu, Kay-Yaw Tay, Kay-Yaw Tay, Kay-Yaw Tay, Wing-Lok Au, Wing-Lok Au, Wing-Lok Au, Eng-King Tan, Eng-King Tan, Eng-King Tan, Louis Chew-Seng Tan, Louis Chew-Seng Tan, Louis Chew-Seng Tan   +25 more
doaj   +1 more source

The Shaking Palsy of the Larynx—Potential Biomarker for Multiple System Atrophy: A Pilot Study and Literature Review

Frontiers in Neurology, 2019
In its early stages multiple system atrophy (MSA), a neurodegenerative movement disorder, can be difficult to differentiate from idiopathic Parkinson's disease (PD), and emphasis has been put on identifying premotor symptoms to allow for its early ...
Tobias Warnecke, Annemarie Vogel, Sigrid Ahring, Doreen Gruber, Doreen Gruber, Hans-Jochen Heinze, Rainer Dziewas, Georg Ebersbach, Florin Gandor, Florin Gandor   +9 more
doaj   +1 more source

Hospital based motor cognitive rehabilitation training. What after? An intervention aimed at patients' support between admissions

Clinical Parkinsonism & Related Disorders
The letter reports on a teleconsultation program for patients with Parkinson's Disease after hospital-based rehabilitation. PwPD and their caregivers were contacted with regular video/phone calls assessing therapy adherence and addressing emerging ...
Anna Carollo, Chiara Siri, Greta Manoni, Margherita Canesi   +3 more
doaj   +1 more source

Uncovering Essential Tremor Genetics: The Promise of Long-Read Sequencing

Frontiers in Neurology, 2022
Long-read sequencing (LRS) technologies have been recently introduced to overcome intrinsic limitations of widely-used next-generation sequencing (NGS) technologies, namely the sequencing limited to short-read fragments (150–300 base pairs).
Luca Marsili, Kevin R. Duque, Rachel L. Bode, Marcelo A. Kauffman, Alberto J. Espay   +4 more
doaj   +1 more source

Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

Neurobiology of Disease, 2014
Exercise has been shown to be beneficial for Parkinson's disease (PD). A major interest in our lab has been to investigate how exercise modulates basal ganglia function and modifies disease progression.
William A. Toy, Giselle M. Petzinger, Brian J. Leyshon, Garnik K. Akopian, John P. Walsh, Matilde V. Hoffman, Marta G. Vučković, Michael W. Jakowec   +7 more
doaj   +1 more source