Results 191 to 200 of about 240,114 (259)

Longitudinal Analysis of Neuroradiological Biomarkers for Fragile X‐Associated Tremor/Ataxia Syndrome and Implications for Clinical Trials

Annals of Neurology, EarlyView.
Objective The objective of this study was to show the capacity of structural brain magnetic resonance imaging (MRI) measures to serve as monitoring biomarkers for Fragile X‐Associated Tremor/Ataxia Syndrome (FXTAS). Methods From 2 longitudinal studies of male FMR1 premutation carriers, 2 brain MRI scans were selected from each participant, collected ...
David Hessl, Jun Yi Wang, Glenda Espinal, Ellery Santos, Flora Tassone, Randi J. Hagerman, Susan M. Rivera   +6 more
wiley   +1 more source

Motor Symptom Variability in Parkinson's Disease: Implications for Personalized Trial Outcomes? [PDF]

Mov Disord
Janssen Daalen J, van der Heiden M, Meinders M, Post B.   +3 more
europepmc   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

A network perspective on cognition in individuals with Parkinson's disease. [PDF]

Alzheimers Dement (Amst)
Scharfenberg D, Kalbe E, Balzer-Geldsetzer M, Berg D, Hilker-Roggendorf R, Kassubek J, Liepelt-Scarfone I, Mollenhauer B, Reetz K, Riedel O, Roeske S, Schulz JB, Storch A, Trenkwalder C, Witt K, Wittchen HU, Dodel R, Ophey A.   +17 more
europepmc   +1 more source

A Single‐Molecule Liposome Assay for Membrane Permeabilisation

Angewandte Chemie International Edition, Accepted Article.
Cell membrane disruption is associated with numerous diseases and underlies the activity of various antimicrobial agents. The rapid screening of compounds capable of disrupting or permeabilising biological membranes is essential to the search for new therapeutic drugs.
Krzysztof Marek Bąk, Daniel Edwards, Dylan George, Bhanu Singh, Ryan Ferguson, Tianxiao Zhao, Kristin Piché, Ariel Louwrier, Scott Lee Cockroft, Mathew Horrocks   +9 more
wiley   +1 more source

Brain age in genetic and idiopathic Parkinson's disease. [PDF]

Brain Commun
Teipel SJ, Hoffmann H, Storch A, Hermann A, Dyrba M, Schumacher J.   +5 more
europepmc   +1 more source

Wearable Biomonitoring with 2D Carbon‐Based Nanocomposite Hydrogels

Advanced Physics Research, EarlyView.
This review critically examines recent advancements in nanocomposite hydrogels, emphasizing the reinforcement mechanisms offered by 2D carbon‐based nanomaterials and exploring the various applications of these hydrogels. Furthermore, it discusses the current challenges and potential avenues for future development and practical implementation of ...
Ning Li, Xiao Xiao, Yu Li, Ruobing Cheng, Junyi Yin, Hulin Zhang, Jun Chen   +6 more
wiley   +1 more source

Therapeutic Potential of Pistachio Green Hull Extract in Treating Parkinson's Disease: A Comprehensive In Vivo and In Vitro Investigation. [PDF]

Food Sci Nutr
Tavakoli M, Mohammadi N, Barzegar M, Valian N, Hosseinmardi N, Sahari MA, Saremi S.   +6 more
europepmc   +1 more source

α-Synuclein Gene Hypomethylation in LRRK2 Parkinson's Disease Patients. [PDF]

Mov Disord
de Mena L, Parés G, Garrido A, Pilco-Janeta DF, Fernández M, Pérez J, Tolosa E, Cámara A, Valldeoriola F, Ezquerra M, Martí MJ, Fernández-Santiago R, Barcelona LRRK2 Study Group.   +12 more
europepmc   +1 more source

Associations of Fire Smoke and Other Pollutants With Incident Rheumatoid Arthritis and Rheumatoid Arthritis–Associated Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to determine whether pollutants such as fire smoke–related particulate matter <2.5 μm (PM2.5) are associated with incident rheumatoid arthritis (RA) and RA‐associated interstitial lung disease (RA‐ILD). Methods This patient–control study used Veterans Affairs (VA) data from October 1, 2009, to December 31, 2018.
Vanessa L. Kronzer, Yangyuna Yang, Punyasha Roul, James L. Crooks, Cynthia S. Crowson, John M. Davis III, Jeffrey A. Sparks, Jeffrey R. Pierce, Katelyn O'Dell, Brian C. Sauer, Grant W. Cannon, Joshua F. Baker, Ted R. Mikuls, Bryant R. England   +13 more
wiley   +1 more source