Results 211 to 220 of about 295,503 (301)

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Variable Speech Cueing Effects in Talkers With Parkinson's Disease. [PDF]

Am J Speech Lang Pathol
Kim D, Tjaden K, Stipancic KL, Ding A, Dietrich MS, Mefferd AS.   +5 more
europepmc   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Commentary on Gut Microbiome-Metabolome Alterations in Advanced Parkinson's Disease With Motor Complications. [PDF]

CNS Neurosci Ther
Rashid H.
europepmc   +1 more source

Cerebral blood flow responses to dorsal and ventral STN DBS correlate with gait and balance responses in Parkinson\u27s disease [PDF]

, 2013
Campbell, Meghan C, Earhart, Gammon M, Flores, Hubert P, Hartlein, Johanna M, Hershey, Tamara, Hill, Kelly K, Karimi, Morvarid, Lugar, Heather M, McNeely, Marie E, Perlmutter, Joel S, Revilla, Fredy J, Tabbal, Samer D, Ushe, Mwiza, Videen, Tom O   +13 more
core   +1 more source

Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models

AGING MEDICINE, EarlyView.
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke, Amrei Vivian Purwien, Annik Steiert, Henrike Hasecke, Yvonne Bouter   +4 more
wiley   +1 more source

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease. [PDF]

Mov Disord
Kofoed RH, Hvingelby VS, Pineda-Pardo JA, Blesa J, Paschen S, Tandon A, Joutsa J, Glud AN.   +7 more
europepmc   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source