Results 231 to 240 of about 295,503 (301)

Machine Learning‐Driven Digital Twin of a Field‐Effect Transistor‐Based Hormone Biosensor for Real‐Time Estradiol Monitoring

Advanced Intelligent Systems, EarlyView.
A machine learning‐driven digital twin simulates an aptamer‐functionalized BioFET measuring 17β‐estradiol. Real‐time Isd signals are processed, features are extracted, and trained models estimate hormone concentration. In parallel, a one‐step‐ahead forward model learns biosensor dynamics and generates realistic synthetic signals, enabling in silico ...
Anastasiia Gorelova, Alexandra Parichenko, Shirong Huang, Santiago Melia, Gianaurelio Cuniberti   +4 more
wiley   +1 more source

Monoaminergic Networks of Cognitive and Behavioral Symptoms in Early Parkinson's Disease. [PDF]

Mov Disord
Niemi KJ, Kaasinen V, Weil RS, Joutsa J.
europepmc   +1 more source

Parkinson's Disease

Neurobiology of Disease, 2000
openaire   +3 more sources

Agricultural Injuries With Dementia: Double Whammy?

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Nearly 40% of US farmers are over 65 years old. Some emerging evidence links agricultural occupational exposure to increased dementia risk. However, little is known about dementia and injury outcomes in agricultural settings. Methods We employed data from the American College of Surgeons Trauma Quality Programs Participant Use File (
Kanika Arora, Jonathan Davis, Lila B. Basnet, Julie Bobitt   +3 more
wiley   +1 more source

Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier, Jodi Warman‐Chardon, Danielle K. Bourque   +2 more
wiley   +1 more source

Detailed Outer Retinal Assessment in Parkinson's Disease Using Directional OCT. [PDF]

Invest Ophthalmol Vis Sci
Lin J, Lee PY, Tran KKN, Finkelstein DI, Bui BV, Nguyen CTO.   +5 more
europepmc   +1 more source

Psychiatric and Cognitive Features in Italian Women With the FMR1 Premutation: A Comprehensive Assessment Using SCID‐5 and Standardized Cognitive Measures

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro, Randi J. Hagerman, Giuseppina Spano, Flora Tassone, Giancarlo Logroscino, Andrea Bosco   +5 more
wiley   +1 more source

Enhanced meta ensemble stacking approach with XGBoost and optuna based detection of Parkinson's disease. [PDF]

Front Digit Health
Joseph Raj AM, Kruthika SL, S A.
europepmc   +1 more source

Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population‐Based Rhineland Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng, Konstantinos Melas, Santiago Estrada, N. Ahmad Aziz, Monique M. B. Breteler   +4 more
wiley   +1 more source

Parkinson's Disease Patient-Specific Striatum Organoids Show Hallmarks of Increased Inflammation. [PDF]

Mov Disord
Barmpa K, Saraiva C, Zagare A, Tuzza M, Longworth J, Zuccoli E, Hufnagel K, Skwirblies F, Schmidt R, Brenner D, Schröder C, Schwamborn JC.   +11 more
europepmc   +1 more source