Results 241 to 250 of about 295,503 (301)

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

An Underrecognized Problem: Missed and Delayed Carbidopa-Levodopa Administration in Emergency Department Patients With Parkinson's Disease. [PDF]

Acad Emerg Med
Elder NM, Lash EM, Tomkins-Tinch C.
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

What can we do to enhance cognitive care in Parkinson's disease? [PDF]

Alzheimers Dement (Amst)
Pourzinal D, Brooks D, O'Sullivan JD, Naismith SL, Dissanayaka NN.   +4 more
europepmc   +1 more source

Epigenetic ageing and the risk of Parkinson's disease. [PDF]

J Neurol Neurosurg Psychiatry
Peng X, Flores-Torres MH, Cortese M, Peng C, Hung AY, Schwarzschild M, Ascherio A, Bjornevik K.   +7 more
europepmc   +1 more source

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease. [PDF]

Mov Disord
Camacho M, Greenland JC, Peattie ARD, Spindler LRB, Holbrook J, Kahanawita L, Fryer TD, Hong YT, Williams-Gray CH.   +8 more
europepmc   +1 more source

An Unusual Motor OFF in Parkinson's Disease. [PDF]

Mov Disord Clin Pract
Jha S, Jog MS.
europepmc   +1 more source