Results 241 to 250 of about 9,423,446 (404)

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

The Progression of NUS1-Associated Parkinson's Disease and the Diagnostic Potential of Plasma NgBR. [PDF]

CNS Neurosci Ther
Li L, Huang J, Xiang Y, Zhang X, Xu Q, Sun Q, Liu Z, Yan X, Li J, Tang B, Guo J.   +10 more
europepmc   +1 more source

Dementia and cognitive impairment in Parkinson's disease. [PDF]

, 1988
F. Girotti, Paola Soliveri, F. Carella, I. Piccolo, Paolo Caffarra, Massimo Musicco, T. Caraceni   +6 more
openalex   +1 more source

Nanoplasmonic Infrared Microarray Sensor Enabling Structural Protein Biomarker‐Based Drug Screening for Neurodegenerative Diseases

Advanced Science, EarlyView.
This work introduces an on‐chip, integrated plasmonic infrared microarray sensor that enables high‐throughput, label‐free drug screening targeting structural protein biomarkers in neurodegenerative diseases. Through ultra‐compact microwell arrays, the sensor achieves ultra‐sensitive, rapid, and multiplexed secondary structural analysis of the effect of
Deepthy Kavungal, Enzo Morro, Senthil T Kumar, Berkay Dagli, Hilal A Lashuel, Hatice Altug   +5 more
wiley   +1 more source

Biopterin in Parkinson's disease. [PDF]

, 1987
A. P. Moore, Peter O. Behan, W. Jacobson, Wilfred L.F. Armarego   +3 more
openalex   +1 more source

The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years

Movement Disorders, 2008
M. Hely, W. Reid, M. Adena, G. Halliday, J. Morris   +4 more
semanticscholar   +1 more source

Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model

Advanced Science, EarlyView.
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis, Elena Capitanini, Karen Kira, Claudia Dell'Amico, Jun Takahashi, Marco Onorati, Fabian Raudzus, Vittoria Raffa   +7 more
wiley   +1 more source

Speech Characteristics Across Motor Subtypes of Parkinson's Disease. [PDF]

Int J Lang Commun Disord
Brzoskowski Dos Santos V, Bressanelli AL, Zardin FV, Rothe-Neves R, Olchik MR.   +4 more
europepmc   +1 more source

Major depression in Parkinson's disease and the mood response to intravenous methylphenidate: possible role of the "hedonic" dopamine synapse. [PDF]

, 1989
Roberto Cantello, Marco Aguggia, M Gilli, M Delsedime, I Chiardo Cutin, A. Riccio, Roberto Mutani   +6 more
openalex   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source