Results 41 to 50 of about 290,866 (278)
Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]
, 2017 Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger +25 more
core +1 more source
Severe Constipation in Parkinson's Disease and in Parkinsonisms: Prevalence and Affecting Factors
Frontiers in Neurology, 2019 Background: constipation is one of the most common and disabling non-motor symptoms of Parkinson Disease (PD) and Parkinsonisms (PS). Few studies evaluate the difference of prevalence between PD and PS and the cause leading to a severe constipation in ...
Giuseppe Frazzitta +4 more
doaj +1 more source
Treatment of dystonia and tics
Clinical Parkinsonism & Related Disorders, 2020 Treatment of dystonia and tics continues to evolve. In dystonia, while oral agents such as benzodiazepines, baclofen and anticholinergics remain in use, botulinum toxin (BoNT) continues to be regarded as the treatment of choice for focal and segmental ...
Steven Bellows, Joseph Jankovic
doaj +1 more source
What contributes to depression in Parkinson's disease? [PDF]
, 2001 Background: Depression is a common problem in patients with Parkinson's disease, but its mechanism is poorly understood. It is thought that neurochemical changes contribute to its occurrence, but it is unclear why some patients develop depression and ...
Jahanshahi, M., Quinn, N.P., Schrag, A.
core +1 more source
Regulation of vesicular trafficking by Parkinson's disease-associated genes
AIMS Molecular Science, 2015 The regulatory mechanisms that control intracellular vesicular trafficking play important roles in cellular function and viability. Neurons have specific vesicular trafficking systems for synaptic vesicle formation, release and recycling.
Tsuyoshi Inoshita, Yuzuru Imai
doaj +1 more source
Understanding health care needs among Veterans with Parkinson's disease: A survey study
Frontiers in Neurology, 2022 Among Veterans, it is estimated that 110,000 are living with Parkinson's disease (PD) in the United States. Whether or not Veterans living with PD are enrolled in the Veterans Health Administration (VHA), they may require special considerations when it ...
Megan Feeney +9 more
doaj +1 more source
Extended Timed Up and Go assessment as a clinical indicator of cognitive state in Parkinson\u27s disease [PDF]
, 2017 Objective: To evaluate a modified extended Timed Up and Go (extended-TUG) assessment against a panel of validated clinical assessments, as an indicator of Parkinson’s disease (PD) severity and cognitive impairment. Methods: Eighty-seven participants with
Anderton, R +7 more
core +2 more sources
Frontiers in Neurology, 2021 Objective: In a prospective study, we investigated the association between physical activity and various motor, non-motor outcomes, and quality of life in early Parkinson's disease (PD) participants in the PD Longitudinal Singapore Study.Background ...
Samuel Yong-Ern Ng +25 more
doaj +1 more source
Everyday walking with Parkinson's disease: understanding personal challenges and strategies [PDF]
, 2008 PURPOSE: This qualitative study was designed to explore the personal experience of everyday walking with Parkinson's disease (PD), the challenges and the strategies employed to compensate for difficulties, to help contextualise the scientific knowledge ...
Birleson, Angela +7 more
core +2 more sources
Mild Cognitive Impairment in Parkinson’s Disease: A Review of Current Concepts
Neurology Research International, 2013 Mild Cognitive Impairment in Parkinson’s Disease (PD-MCI) is common and may be associated with accelerated progression to dementia. Considering the importance of this emerging entity, new diagnostic criteria have recently been proposed. Early recognition
Natalie C. Palavra +2 more
doaj +1 more source