Results 41 to 50 of about 322,457 (214)

Barriers to reporting non-motor symptoms to health-care providers in people with Parkinson's [PDF]

, 2019
Background: Non-motor symptoms (NMS) are common in Parkinson's disease (PD) and cause significant distress. A high rate of non-declaration of NMS by patients to healthcare providers (HCP) means that many NMS remain untreated. Current understanding of the
Brown, R. G., Chaudhuri, K. R., Hurt, C. S., Moss-Morris, R., Rixon, L., Samuel, M.   +5 more
core   +3 more sources

Psychogenic Tremor: A Video Guide to Its Distinguishing Features

Tremor and Other Hyperkinetic Movements, 2014
Background: Psychogenic tremor is the most common psychogenic movement disorder. It has characteristic clinical features that can help distinguish it from other tremor disorders.
Joseph Jankovic, Mary Ann Thenganatt
doaj   +1 more source

Quantitative analysis of language production in Parkinson's disease using a cued sentence generation task [PDF]

, 2012
The present study examined language production skills in Parkinson's disease (PD) patients. A unique cued sentence generation task was created in order to reduce demands on memory and attention.
Corthals, Paul, De Letter, Miet, Santens, Patrick, Van Borsel, John, Vanhoutte, Sarah   +4 more
core   +1 more source

Frequency of Non-motor Symptoms in Parkinson's Patients With Motor Fluctuations

Frontiers in Neurology, 2021
Background: Non-motor symptoms (NMS), including neuropsychiatric, sleep, autonomic, and sensory domains, are an integral aspect of the clinical presentation of Parkinson disease (PD) and affect neurocognitive functioning as well as patients' and ...
Mariana Fernandes, Mariangela Pierantozzi, Mariangela Pierantozzi, Alessandro Stefani, Alessandro Stefani, Carlo Cattaneo, Erminio A. Bonizzoni, Rocco Cerroni, Nicola Biagio Mercuri, Nicola Biagio Mercuri, Claudio Liguori, Claudio Liguori, Claudio Liguori   +12 more
doaj   +1 more source

Spatial judgment in Parkinson's disease: Contributions of attentional and executive dysfunction [PDF]

, 2019
Spatial judgment is impaired in Parkinson's disease (PD), with previous research suggesting that disruptions in attention and executive function are likely contributors.
Cronin-Golomb, Alice, Moon, Kathryn L.M., Neargarder, Sandy, Salazar, Robert D.   +3 more
core   +1 more source

Laserlight visual cueing device for freezing of gait in Parkinson's disease: a case study of the biomechanics involved [PDF]

, 2015
Background: Freezing of gait (FOG) is a serious gait disorder affecting up to two-thirds of people with Parkinson's disease (PD). Cueing has been explored as a method of generating motor execution using visual transverse lines on the floor.
B. Evans, C. J. Egerton, Fahn S, Gerstmann J, J. D. Richards, J. Janssen, P. McCandless, Richards J   +7 more
core   +1 more source

Neuroprotection and Functional Recovery Associated with Decreased Microglial Activation Following Selective Activation of mGluR2/3 Receptors in a Rodent Model of Parkinson's Disease

Parkinson's Disease, 2010
Clinical trials have demonstrated positive proof of efficacy of dual metabotropic glutamate receptor 2/3 (mGluR2/3) agonists in both anxiety and schizophrenia.
Hugh Chan, Helen Paur, Anthony C. Vernon, Virginia Zabarsky, Krishna P. Datla, Martin J. Croucher, David T. Dexter   +6 more
doaj   +1 more source

Resveratrol suppresses the growth and metastatic potential of cervical cancer by inhibiting STAT3Tyr705 phosphorylation

Cancer Medicine, 2020
Aberrant signal transducer and activator of transcription 3 (STAT3) signaling promotes the initiation and progression of cancer in humans by either inhibiting apoptosis or inducing cell proliferation, angiogenesis, invasion, and metastasis.
Xiaodong Sun, Qianqian Xu, Lian Zeng, Lixia Xie, Qiang Zhao, Hongxia Xu, Xuanbin Wang, Nan Jiang, Pan Fu, Ming Sang   +9 more
doaj   +1 more source

Computational analysis of the LRRK2 interactome. [PDF]

, 2015
LRRK2 was identified in 2004 as the causative protein product of the Parkinson's disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson's disease, alongside one ...
Denny, P, Lewis, PA, Lovering, RC, Manzoni, C   +3 more
core  

Common Genetic Variant Association with Altered HLA Expression, Synergy with Pyrethroid Exposure, and Risk for Parkinson's Disease: An Observational and Case-Control Study. [PDF]

, 2015
Background/objectivesThe common non-coding single nucleotide polymorphism (SNP) rs3129882 in HLA-DRA is associated with risk for idiopathic Parkinson's disease (PD).
Boss, JM, Bronstein, J, Chang, J, Chung, J, Cook, DA, Factor, SA, Kannarkat, GT, Lee, J-K, Paul, KC, Ritz, B, Sandy, E, Tansey, MG   +11 more
core   +2 more sources