Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]
Benitez, Bruno A +11 more
core +2 more sources
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia. [PDF]
Real R +20 more
europepmc +1 more source
Commentary: Three questions for the study of traumatic brain injury in animals
The Anatomical Record, EarlyView.
Gregory Hollin
wiley +1 more source
Effects of Deep Brain Stimulation on Adductor Laryngeal Dystonia
This study evaluated how globus pallidus interna (GPi) versus ventral intermediate nucleus (VIM) deep brain stimulation (DBS) affects objective voice measures in patients with adductor laryngeal dystonia. GPi‐DBS was associated with greater improvements in voicing, voice breaks, and intensity modulation, while VIM‐DBS showed greater improvement in ...
Rita R. Patel +11 more
wiley +1 more source
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Multi-regional alterations in glucose and purine metabolic pathways in the Parkinson's disease dementia brain. [PDF]
Scholefield M +5 more
europepmc +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi +7 more
wiley +1 more source
Neurofilament light chain is increased in the parahippocampal cortex and associates with pathological hallmarks in Parkinson's disease dementia. [PDF]
Frigerio I +11 more
europepmc +1 more source

