Results 151 to 160 of about 472,711 (314)

Concomitant Alzheimer Disease Pathology in Parkinson Disease Dementia. [PDF]

Ann Neurol, 2023
Tropea TF, Albuja I, Cousins KAQ, Irwin DJ, Lee EB, Chen-Plotkin AS.   +5 more
europepmc   +1 more source

Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice

Annals of Neurology, EarlyView.
Objective Traumatic brain injury (TBI) is an established risk factor for dementia, although the underlying mechanisms remain unclear. Our previous research demonstrated that a single severe TBI in wild‐type (WT) mice induces a prion‐like form of tau (tauTBI) that spreads throughout the brain, leading to memory deficits.
Gloria Vegliante, Francesca Pischiutta, Elena Restelli, Federico Moro, Maria Antonietta Chiaravalloti, Ilaria Raimondi, Ilaria Bertani, Ilaria Lisi, Eliana Sammali, Rosaria Pascente, Serena Scozzari, Laura Pasetto, Carly Douglas, Marco Locatelli, Fabrizio Ortolano, Valentina Bonetto, David J. Loane, Nino Stocchetti, Roberto Chiesa, Elisa R. Zanier   +19 more
wiley   +1 more source

Clinical and Biological Determinants of Longitudinal Cognitive Function in Patients With GBA1 Variants and Subthalamic Deep Brain Stimulation

Annals of Neurology, EarlyView.
Objective Whether cognitive decline in patients with Parkinson's disease (PD) carrying GBA1 variants is accelerated after subthalamic deep brain stimulation (STN‐DBS) remains controversial. Clarifying long‐term cognitive outcomes is essential for informed decision making.
Moritz A. Loeffler, Philipp Klocke, Isabel Wurster, Stefanie Lerche, Idil Cebi, Thomas Gasser, Alireza Gharabaghi, Kathrin Brockmann, Daniel Weiss   +8 more
wiley   +1 more source

Speech Biomarkers From Smartphone Calls Track Progression in REM Sleep Behavior Disorder and Parkinson's Disease

Annals of Neurology, EarlyView.
Objective This 24‐month longitudinal study involving isolated rapid eye movement sleep behavior disorder (iRBD), early‐stage Parkinson's disease (PD), and matched healthy control subjects aimed to assess whether acoustic speech features from real‐world smartphone calls provide passive progressive biomarkers in synucleinopathies.
Michal Šimek, Tereza Tykalová, Michal Novotný, Vojtěch Illner, Tomáš Kouba, Martin Šubert, Pavel Sovka, Jan Švihlík, Evžen Růžička, Karel Šonka, Petr Dušek, Jan Rusz   +11 more
wiley   +1 more source

Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force

Movement Disorders, 2007
B. Dubois, D. Burn, C. Goetz, D. Aarsland, Richard G. Brown, G. Broe, D. Dickson, C. Duyckaerts, J. Cummings, S. Gauthier, A. Korczyn, A. Lees, R. Levy, I. Litvan, Y. Mizuno, I. McKeith, C. Olanow, W. Poewe, C. Sampaio, E. Tolosa, M. Emre   +20 more
semanticscholar   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia. [PDF]

Brain, 2023
Real R, Martinez-Carrasco A, Reynolds RH, Lawton MA, Tan MMX, Shoai M, Corvol JC, Ryten M, Bresner C, Hubbard L, Brice A, Lesage S, Faouzi J, Elbaz A, Artaud F, Williams N, Hu MTM, Ben-Shlomo Y, Grosset DG, Hardy J, Morris HR.   +20 more
europepmc   +1 more source

Moving beyond neurophobia to cultivate the neuroquisitive learner

Anatomical Sciences Education, EarlyView.
Abstract “Neurophobia,” a pervasive fear of the neurological sciences, poses a significant barrier in medical education, affecting learners and physicians worldwide. Its consequences are far‐reaching, contributing to a limited neurology workforce and diminished confidence among non‐specialists in managing neurological conditions.
Joanna R. Appel, Kirsten A. Porter‐Stransky   +1 more
wiley   +1 more source

Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults

Autism Research, EarlyView.
ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang, Hang Qu, Danielle Christensen, Hanna M. Gemmell, Ellen M. Parks, Kyla E. Wetherington, Ann‐Marie Orlando, Regilda A. Romero, Bikram Karmakar, David E. Vaillancourt   +9 more
wiley   +1 more source

Multi-regional alterations in glucose and purine metabolic pathways in the Parkinson's disease dementia brain. [PDF]

NPJ Parkinsons Dis, 2023
Scholefield M, Church SJ, Taylor G, Knight D, Unwin RD, Cooper GJS.   +5 more
europepmc   +1 more source