Results 241 to 250 of about 125,678 (274)

Lack of Cerebrospinal Fluid α‐Synuclein Seeding in VPS35 D620N‐ and LRRK2 Y1699C‐Linked Parkinson's Disease

Movement Disorders, EarlyView.
Letizia Santinelli, Neringa Pratuseviciute, Lara M. Lange, Teresa Kleinz, Norbert Brüggemann, Linn Streubel‐Gallasch, Meret Möller, Alexander Zimprich, Christof Brücke, Jean‐Marc Good, Norman Griebner, Shalini Padmanabhan, Philip Seibler, Peter Bauer, Wim Vandenberghe, Esther Sammler, Cornelis Blauwendraat, Christine Klein, Max Borsche   +18 more
wiley   +1 more source

Involuntary Clozapine Treatment: A Systematic Review

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction We aimed to synthesize the information relevant for clinical practice on involuntary clozapine treatment. Methods Articles were identified with MEDLINE, Web of Sciences and PsycINFO search from inception through September 2025 (PROSPERO database registration CRD420251234475).
Hélène Verdoux, Alexis Lepetit, Peter F. J. Schulte   +2 more
wiley   +1 more source

Primary open‐angle glaucoma as a marker of upcoming Alzheimer's disease: A 20‐year Danish National Registry‐Based Study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate whether primary open‐angle glaucoma (POAG) is associated with an increased long‐term risk of developing Alzheimer's disease, given its shared neurodegenerative features. Methods A 20‐year longitudinal, registry‐based matched cohort study was conducted using Danish national health registries from 1998 to 2018. Individuals
Cecilia Kronvold, Signe Sperling, Sören Möller, Jakob Grauslund, Lonny Stokholm   +4 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Alzheimer's disease and mixed pathologies as a hidden contributor to fatal hypothermia: A large‐scale forensic autopsy‐based study

Brain Pathology, EarlyView.
We investigated neuropathological manifestations of hypothermia in 168 cases. Patients aged 65 years or more constituted 80% of the total cohort. Alzheimer's disease was the most common comorbidity, affecting 40% of all patients. Abstract There is a paucity of autopsy‐based studies providing detailed neuropathological characteristics of fatal ...
Shojiro Ichimata, Koji Yoshida, Ryo Tanaka   +2 more
wiley   +1 more source

Frontotemporal dementia: Clinical aspects, genetics, and neuropathology of a family with a C9ORF72 expansion in Argentina

Brain Pathology, EarlyView.
Immunohistochemistry for TDP‐43: (A)—Dentate gyrus; (B)—Temporal lobe. Abstract Frontotemporal dementia (FTD) is the second most common cause of early‐onset dementia, typically manifesting before the age of 65, with a mean onset at 58 years. FTD may encompass a spectrum of neurodegenerative disorders resulting from frontotemporal lobar degeneration ...
Karen Daniela Román, Carolina Agata Ardohain, Ezequiel I. Surace, Mónica Beatriz Mezmezian, Alejandro Levy, Alice Baez Lovera, Carlos Turizo, Marcos G. Sorbara, María M. Esnaola y Rojas, Gastón H. Graviotto, Gustavo Sevlever, Ricardo F. Allegri, Cecilia M. Serrano, Nahuel Magrath Guimet   +13 more
wiley   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source

Physical Activity Patterns and Brain Health: A Systematic Review About Weekend Warrior vs Regular Exercise on Neuropsychiatric Disorders. [PDF]

Am J Lifestyle Med
Moraes de Oliveira G, Nardelli da Silva AB, Reis Barreto ES, Antunes Júnior CR, Adalier E, Valeriano Zamora F, Frates E, Mansur NSB, Medina G.   +8 more
europepmc   +1 more source

Potential protein blood-based biomarkers for cognitive dysfunction in Parkinson's disease: a systematic review and network meta-analysis. [PDF]

Front Aging Neurosci
Tu Y, Lu C, Wu B, Yang Y, Li J, Su Q, Zhao Z.   +6 more
europepmc   +1 more source

Best practice guidelines for the diagnosis, evaluation, and management of cognitive disorders in Parkinson's disease. [PDF]

Age Ageing
Pourzinal D, Brooks D, Sriram D, Mccann E, King JM, Pachana NA, Shrubsole K, Wood B, Lehn A, Marsh R, Liddle J, Mitchell LK, O'Sullivan JD, Tan ECK, Page N, Lobo EH, Verreynne ML, Lenzen S, Dissanayaka N.   +18 more
europepmc   +1 more source