Results 51 to 60 of about 68,677 (270)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Public opinion on primary prevention of dementia, multiple sclerosis and Parkinson’s disease [PDF]

This is a policy briefing produced by the NIHR Dementia and Neurodegeneration Policy Research Unit at Queen Mary University of London (DeNPRU-QM). Summary Neurodegenerative diseases such as dementia, multiple sclerosis and Parkinson’s disease are amongst
Marshall, CR, Kenten, C, Carroll on behalf of DeNPRU-QM, C, Browning, S, Pouncey, T, Mukadam, N, Schott, J, Horne, R, Thomson, A, Cooper, C, Carr, G, Rauf, M, Dobson, R, Banerjee, S   +13 more
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Interlinking dementia in Parkinson's disease: nutritional correlates of body composition

, 2020
Little evidence showed that body composition has a primary role in the development of dementia in Parkinson’s disease (PD). However, several studies indicated that metabolic and nutritional dysfunctions have a relevant influence on disease outcome.
Jéssica Emy Komuro, Arthur Oscar Schelp, José Eduardo Corrente, Komuro, Jéssica Emy, Schelp, Arthur Oscar [UNESP], Silvia Justina Papini, Corrente, José Eduardo, Papini, Silvia Justina   +7 more
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Rural-urban differences in the effects on mental well-being of caring for people with stroke or dementia [PDF]

, 2007
Background: Rural and urban differences in the effects of care-giving are not well documented. This paper reports data on 122 carers for people with stroke or dementia living in rural and urban settings in Wales.
Woods, R., Russell, I., Reeves, Carla, Robinson, C.A., Russell, I.T., Tommis, Y., Woods, R.T., Robinson, C.A.; id_orcid, Seddon, D., Reeves, C.   +9 more
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Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease

BMC Medicine, 2007
Background Statins are a class of medications that reduce cholesterol by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Whether statins can benefit patients with dementia remains unclear because of conflicting results.
Li Nien-Chen, Wang Stanley W, Wolozin Benjamin, Lee Austin, Lee Todd A, Kazis Lewis E   +5 more
doaj   +1 more source

Investigating the interaction between neuropsychiatry features and daily activities on social function in patients with Parkinson's disease with mild cognitive impairment

BJPsych Open, 2022
Background Social functioning is crucial for daily living and is an essential indicator of dementia in patients with Parkinson's disease. The pattern of social functioning in patients with Parkinson's disease without dementia (i.e.
Yi-Ru Chen, Chun-Hsiang Tan, Hui-Chen Su, Chung-Yao Chien, Pi-Shan Sung, Tien-Yu Lin, Tsung-Lin Lee, Rwei-Ling Yu   +7 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Costs of Parkinson's Disease and Antiparkinsonian Pharmacotherapy: An Italian Cohort Study [PDF]

, 2010
Objective: Antiparkinsonian pharmacotherapy is costly and the determinants of drug costs in Parkinson's disease (PD) have been poorly investigated. The objective of this study was to investigate the costs of PD and antiparkinsonian drugs in an Italian ...
Katia Longo, Oertel, Wolfgang H., Bötzel, Kai, Yaroslav Winter, Karla Eggert, Paolo Barone, Balzer-Geldsetzer, Monika, Kai Boetzel, Dodel, Richard, Longo, Katia, Jens P. Reese, Wolfgang H. Oertel, Sonja von Campenhausen, Giuseppe Spiga, Campenhausen, Sonja von, Winter, Yaroslav, Richard Dodel, Reese, Jens P., Barone, Paolo, Spiga, Giuseppe, Eggert, Karla, Monika Balzer-Geldsetzer   +21 more
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Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Cognitive deficits and structural brain changes associated with dementia and visual hallucinations in Parkinson's disease [PDF]

, 2006
[eng] Cognitive impairment of different degrees and hallucinations are common complications of chronic Parkinson's disease (PD). The pathogenesis, pathophysiology, and relationship between cognitive deficits and presence of hallucinations are not fully ...
Ramírez Ruiz, Blanca
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