Results 121 to 130 of about 693,546 (355)

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Cognitive Behavioral Therapy in Movement Disorders. A Review [PDF]

open access: yes, 2015
In addition to motor symptoms, patients with movement disorders often complain of psychiatric disturbances, including mood, anxiety, and impulse-control disorders and psychosis.
Berardelli, Alfredo   +5 more
core   +1 more source

Study of Swiss-Ball Exercises Effectiveness on Improvement of Balance and Depression of Patients with Parkinson Disease

open access: yesمجله پژوهش در علوم توانبخشی, 2008
• Background:Parkinson's disease is a progressive and degenerative disease of the basal ganglia of the brain. Four major signs of this disease are: bradykinesia, tremor, rigidity and postural instability. Postural instability is the main cause of falling
E Ghasemi   +4 more
doaj   +1 more source

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham   +19 more
wiley   +1 more source

Es el reflejo glabelar un componente del parkinsonismo inducido por neurolépticos?

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2005
Introducción. La evidencia disponible sugiere que algunos signos neurológicos atribuidos al uso de neurolépticos son realmente manifestaciones secundarias de trastornos psicóticos. Objetivo.
Ricardo Sánchez   +2 more
doaj   +1 more source

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease. [PDF]

open access: yesAnn Neurol
Objective Lewy body disease (LBD) is a complex neurodegenerative disorder characterized by the accumulation of misfolded α‐synuclein in the brain. Neuroinflammation has long been implicated in LBD pathogenesis, and recent genetic studies in Parkinson's disease (a clinical manifestation of LBD) have shown consistent association with the human leukocyte ...
Gavrielatos M   +34 more
europepmc   +2 more sources

Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson’s Disease? [PDF]

open access: yesBiomolecules, 2015
Currently, the pathophysiology of idiopathic Parkinson’s disease is explained by a loss of mainly dopaminergic nerve cells that causes a neurotransmitter deficiency. In the final stage of the disease, there is a marked loss of neurons in the substantia nigra.
openaire   +3 more sources

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Association of metabolic syndrome and change in Unified Parkinson\u27s Disease Rating Scale scores. [PDF]

open access: yes, 2017
OBJECTIVE: To explore the association between metabolic syndrome and the Unified Parkinson\u27s Disease Rating Scale (UPDRS) scores and, secondarily, the Symbol Digit Modalities Test (SDMT).
Bainbridge, Jacquelyn L.   +14 more
core   +1 more source

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