Results 181 to 190 of about 119,702 (338)

Editorial: Exercise and neuroplasticity in Parkinson disease. [PDF]

open access: yesFront Neurol
Hirsch MA, Dalgas U, van Wegen EEH.
europepmc   +1 more source

Parkinson Disease [PDF]

open access: yesMayo Clinic Proceedings, 2016
Rachael A, Vaubel   +2 more
openaire   +2 more sources

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

open access: yesAdvanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu   +15 more
wiley   +1 more source

3‐[3‐(Phenalkylamino)cyclohexyl]phenols: Synthesis, biological activity, and in silico investigation of a naltrexone‐derived novel class of MOR‐antagonists

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Based on a simplified version of the morphinan scaffold, 3‐[3‐(phenalkylamino)cyclohexyl]phenol analogues were designed, synthesized and evaluated for their µ‐opioid receptor (MOR) antagonist activity in vitro and in silico. Docking studies indicate a peculiar combination of C‐1 stereochemistry and N‐substitutions as feasibly essential for MOR‐ligand ...
Graziella Tocco   +8 more
wiley   +1 more source

Impact of pimavanserin on prescribing practices in parkinson disease. [PDF]

open access: yesClin Park Relat Disord
Pham Nguyen TP   +3 more
europepmc   +1 more source

14-3-3 Proteins in Lewy Bodies in Parkinson Disease and Diffuse Lewy Body Disease Brains [PDF]

open access: bronze, 2002
Yasuhiro Kawamoto   +5 more
openalex   +1 more source

Micro‐Coil Neuromodulation at Single‐Cell and Circuit Levels for Inhibiting Natural Neuroactivity, Neutralizing Electric Neural Excitation, and Suppressing Seizures

open access: yesAdvanced Science, EarlyView.
Micromagnetic stimulation (µMS) offers a precise method for neural inhibition, complementing existing neuromodulation techniques. Using an implantable micro‐coil device, µMS selectively suppresses cortical activity with high spatial resolution. It effectively counteracts micro‐electrode stimulation and reduces seizure amplitude, highlighting its ...
Kayeon Kim   +11 more
wiley   +1 more source

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