Results 221 to 230 of about 271,759 (355)
Using Magnetoencephalography to Advance the Science of Parkinson Disease: A Systematic Review. [PDF]
Kariv S +5 more
europepmc +1 more source
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu +5 more
wiley +1 more source
Erratum: Mutations in NR4A2 associated with familial Parkinson disease [PDF]
Le Wang +6 more
openalex +1 more source
Neural networks reveal novel gene signatures in Parkinson disease from single-nuclei transcriptomes. [PDF]
Fiorini MR +4 more
europepmc +1 more source
Single‐molecule fluorescence microscopy is combined with proteomic profiling to fingerprint the morphology and composition of TDP‐43 protein aggregates found in post‐mortem motor neuron disease brain tissues. Aggregate fingerprints can distinguish disease from control donors and detect unexpected TDP‐43 pathology in SOD1‐MND.
Dezerae Cox +9 more
wiley +1 more source
Correlates of Loneliness in Parkinson Disease During the COVID-19 Pandemic: A Longitudinal Study. [PDF]
de Figueiredo JM +5 more
europepmc +1 more source
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source

