Results 221 to 230 of about 119,702 (338)

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

Research Progress of Camptocormia in Parkinson Disease. [PDF]

Clin Spine Surg
Lu Y, Zhang X, Li J, Li W, Yu M.
europepmc   +1 more source

Bridging Mechanical Properties with Atomic Structures of Polymorphic α‐Synuclein Fibrils by Single‐Molecule Analysis and Molecular Dynamics Simulations

Aggregate, EarlyView.
α‐Synuclein fibrils exhibit distinct mechanical properties influencing their neurotoxicity and pathogenicity in synucleinopathies like Parkinson's disease. Combining optical tweezers and molecular dynamics simulations, this study builds the structure–mechanics relationships of wild‐type and two disease‐associated mutants E46K and A53T α‐Synuclein ...
Lulu Bi, Linge Li, Xiang Li, Shaojuan Wu, Xia Zhang, Yilin Zhao, Dan Li, Cong Liu, Zhonghuai Hou, Bo Sun   +9 more
wiley   +1 more source

Dopamine Transporter Brain Imaging to Assess the Effects of Pramipexole vs Levodopa on Parkinson Disease Progression

, 2002
Parkinson Study Group
openalex   +1 more source

Erratum: Mutations in NR4A2 associated with familial Parkinson disease [PDF]

, 2003
Le Wang, Pengfei Xu, Joseph Jankovic, Haowei Jiang, Stanley H. Appel, Richard Smith, Demetrios K. Vassilatis   +6 more
openalex   +1 more source

Multi‐Risk‐Level Sarcopenia‐Prone Screening via Machine Learning Classification of Sit‐to‐Stand Motion Metrics from Wearable Sensors

Advanced Intelligent Systems, EarlyView.
A machine learning approach utilizes micro inertial measurement units (μIMUs) for noninvasive sarcopenia screening through a sit‐to‐stand test. With 53 older participants wearing IMUs, 510 features are extracted across four motion phases. Five algorithms (support vector machine, K‐nearest neighbors, decision tree, linear discriminant analysis, and ...
Keer Wang, Hongyu Zhang, Clio Yuen Man Cheng, Meng Chen, King Wai Chiu Lai, Calvin Kalun Or, Yong Hu, Arul Lenus Roy Vellaisamy, Cindy Lo Kuen Lam, Ning Xi, Vivian Weiqun Lou, Wen Jung Li   +11 more
wiley   +1 more source

Natural History of NAA15‐Related Neurodevelopmental Disorder Through Adolescence

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The NatA N‐terminal acetyltransferase complex is composed of the NAA10 catalytic subunit and the auxiliary subunits NAA15 and HYPK. While those with variants in the enzymatic subunit develop Ogden Syndrome, individuals with variants in the NAA15 coding region develop NAA15‐related neurodevelopmental syndrome, which presents with a wide array ...
Rikhil Makwana, Carolina Christ, Rahi Patel, Elaine Marchi, Randie Harpell, Gholson J. Lyon   +5 more
wiley   +1 more source

Parkinson disease - Prevalence, trends and regional patterns in Germany. An analysis based on routine data from the statutory health insurance. [PDF]

J Health Monit
Rommel A, Deuschl G, Dodel R, Yessimova D, Neuhauser H, Brückner G, Schröder H, Schüssel K, Porst M.   +8 more
europepmc   +1 more source

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore, Gianmichele Migaleddu, Pei‐Chien Tsai, Antonella Fogli, Maria Adelaide Caligo, Gabriele Siciliano, Mirco Cosottini, Yi‐Chung Lee, Yi‐Chu Liao, Michelangelo Mancuso, Roberto Ceravolo, Daniela Frosini   +11 more
wiley   +1 more source

Understanding Parkinson disease in Spain: Genetic and clinical insights. [PDF]

Eur J Neurol
Gómez-Garre P, Martín-Bórnez M, Muñoz-Delgado L, Díaz-Belloso R, Periñán MT, Bonilla-Toribio M, Buiza-Rueda D, Macías-García D, Jesús S, Adarmes-Gómez A, Ojeda E, Luque-Ambrosiani A, García-Díaz S, Sánchez RP, Carrillo F, Mir P.   +15 more
europepmc   +1 more source