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Bradysomnia in Parkinson’s disease
Clinical Neurophysiology, 2016Polysomnography studies in Parkinson's disease (PD) patients show altered sleep microstructure with decreased level of arousability, indicating impaired sleep-wake dynamics in PD. The aim of this study was to investigate dynamical aspects of sleep EEG in PD as compared to healthy controls.In this retrospective, controlled study, we applied a previously
Imbach, Lukas L +6 more
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James Parkinson: Parkinson's Disease
Journal of Perioperative Practice, 2013Parkinson's disease is a condition that anyone with a modicum of medical knowledge can recognise in the street - as indeed how it was studied by James Parkinson himself. Its three characteristic features are: 1. Increase in the tone of the voluntary muscles (rigidity). 2. Slowness of movement (bradykinesis). 3.
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The Lancet, 2015
Parkinson's disease is a neurological disorder with evolving layers of complexity. It has long been characterised by the classical motor features of parkinsonism associated with Lewy bodies and loss of dopaminergic neurons in the substantia nigra. However, the symptomatology of Parkinson's disease is now recognised as heterogeneous, with clinically ...
Lorraine V, Kalia, Anthony E, Lang
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Parkinson's disease is a neurological disorder with evolving layers of complexity. It has long been characterised by the classical motor features of parkinsonism associated with Lewy bodies and loss of dopaminergic neurons in the substantia nigra. However, the symptomatology of Parkinson's disease is now recognised as heterogeneous, with clinically ...
Lorraine V, Kalia, Anthony E, Lang
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Journal of Neurology, 1986
Advanced Parkinson's disease (PD) is frequently associated with dementia. The pathogenesis of this dementia is complex, related to deficiency of several biogenic amines and cortical Lewy body deposition, as well as co-existent age-related brain changes, both of the Alzheimer's type and vascular.
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Advanced Parkinson's disease (PD) is frequently associated with dementia. The pathogenesis of this dementia is complex, related to deficiency of several biogenic amines and cortical Lewy body deposition, as well as co-existent age-related brain changes, both of the Alzheimer's type and vascular.
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2018
Parkinson disease (PD) is a complex, multisystem disorder with both neurologic and systemic nonmotor manifestations. It is neurodegenerative in nature in which disordered balance, gait, and falls are universal problems that can be present at initial diagnosis, and which progress over time.
Samuel D, Kim +3 more
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Parkinson disease (PD) is a complex, multisystem disorder with both neurologic and systemic nonmotor manifestations. It is neurodegenerative in nature in which disordered balance, gait, and falls are universal problems that can be present at initial diagnosis, and which progress over time.
Samuel D, Kim +3 more
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Inflammation and immune dysfunction in Parkinson disease
Nature Reviews Immunology, 2022Malú Gámez Tansey +2 more
exaly
Parkinson's disease, Parkinsonism and aging
Archives of Gerontology and Geriatrics, 2002NICITA MAURO, Vittorio +5 more
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Parkinson disease-associated cognitive impairment
Nature Reviews Disease Primers, 2021Dag Aarsland +2 more
exaly
Parkinsonism and Parkinson's Disease
New England Journal of Medicine, 1996Carlos Singer +2 more
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