Results 231 to 240 of about 274,716 (345)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Parkinson Disease <i>SNCA</i> Risk Variants Are Associated With Higher Asymmetric Putamen Dopaminergic Dysfunction. [PDF]

Neurol Genet
Alhusaini S, Dayanim G, Kandil M, Krohn L, Molino J, Gan-Or Z, Dagher A.   +6 more
europepmc   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

Advanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna, Jinshan He, Jiaxing Miao, Nargis Shaheen, Boyu Xia, Cankun Wang, Qin Ma, Matthew C Bernier, Bryan A Whitson, Nuo Sun, Jing Zhao, Yutong Zhao   +11 more
wiley   +1 more source

Risk of Parkinson Disease Among Patients With Restless Leg Syndrome.

JAMA Netw Open
Bang M, Park D, Kim JH, Kim HS.
europepmc   +1 more source

Neural networks reveal novel gene signatures in Parkinson disease from single-nuclei transcriptomes. [PDF]

NPJ Parkinsons Dis
Fiorini MR, Li J, Fon EA, Farhan SMK, Thomas RA.   +4 more
europepmc   +1 more source

Activation of subthalamic neurons by contralateral subthalamic deep brain stimulation in Parkinson disease

, 2010
Harrison C. Walker, Ray L. Watts, Christian J. Schrandt, He Huang, Stephanie Guthrie, Barton L. Guthrie, Erwin B. Montgomery   +6 more
openalex   +2 more sources

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Exploring behavior, motivation, and barriers to exercise in Parkinson disease. [PDF]

Clin Park Relat Disord
Haussler AM, Baudendistel ST, Tueth LE, Earhart GM.   +3 more
europepmc   +1 more source

Validation study of the Parkinson’s Fatigue Scale in advanced Parkinson’s disease

, 2019
Pablo Martínez‐Martín, Wetmore JB, Arbelo JM, Catalán Alonso Mj, Francesc Valldeoriola, Carmen Rodríguez‐Blázquez   +5 more
openalex   +1 more source

Cognitive impairment in carriers of glucocerebrosidase gene mutation in Parkinson disease patients

, 2014
Michalina Malec‐Litwinowicz, Monika Rudzińska, Michał Szubiga, Michał Michalski, Tomasz Tomaszewski, Andrzej Szczudlik   +5 more
openalex   +2 more sources