Results 231 to 240 of about 9,346,254 (401)

Gradient Solvent Replacement‐Mediated Formation of High‐Strength Hydrogel‐Forming Microneedle for Long‐Term Drug Delivery

open access: yesAdvanced Science, EarlyView.
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li   +12 more
wiley   +1 more source

Data-Driven Subtypes of Parkinson Disease Based on Dopamine Responsiveness. [PDF]

open access: yesCNS Neurosci Ther
Wang JY   +14 more
europepmc   +1 more source

Linkage of Parkinsonism and Alzheimer's disease with Lewy body pathology to chromosome 12 [PDF]

open access: bronze, 2002
William K. Scott   +3 more
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

The modifying effect of mutant LRRK2 on mutant GBA1-associated Parkinson disease. [PDF]

open access: yesHum Mol Genet
Serebryany-Piavsky V   +6 more
europepmc   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

Impact of pimavanserin on prescribing practices in parkinson disease. [PDF]

open access: yesClin Park Relat Disord
Pham Nguyen TP   +3 more
europepmc   +1 more source

Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]

open access: yes, 2018
Benitez, Bruno A   +11 more
core   +2 more sources

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