Results 101 to 110 of about 65,159 (298)
Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov +7 more
wiley +1 more source
Further focus on the study of freezing of gait
DOI: 10.3969/j.issn.1672-6731.2017.02 ...
Xian-wen CHEN
doaj
Abstract Objective To evaluate the effects of bilateral caudal zona incerta (cZi) deep brain stimulation (DBS) for Parkinson's disease (PD) one year after surgery and to create anatomical improvement maps based on patient‐specific simulation of the electric field.
Rasmus Stenmark Persson +6 more
wiley +1 more source
Diagnosis and treatment of impulse control disorders in patients with movement disorders
Impulse control disorders are a psychiatric condition characterized by the failure to resist an impulsive act or behavior that may be harmful to self or others.
Tiago A. Mestre +4 more
doaj +1 more source
Glucocerebrosidase involvement in Parkinson Disease and other Synucleinopathies
Mutations in the both copies (homozygous or compound heterozygous) of the gene encoding the lysosomal enzyme glucocerebrosidase, which cleaves the glycolipid glucocerebroside into glucose and ceramide causes Gaucher Disease. However, multiple independent
Maria Rosario Almeida
doaj +1 more source
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange +8 more
wiley +1 more source
Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction
Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam +15 more
wiley +1 more source
Neural Dynamics in Parkinsonian Brain:The Boundary Between Synchronized and Nonsynchronized Dynamics
Synchronous oscillatory dynamics is frequently observed in the human brain. We analyze the fine temporal structure of phase-locking in a realistic network model and match it with the experimental data from parkinsonian patients.
A. Pikovsky +7 more
core +1 more source
Randomized controlled trial of a home-based action observation intervention to improve walking in Parkinson disease [PDF]
Published in final edited form as: Arch Phys Med Rehabil. 2016 May ; 97(5): 665–673. doi:10.1016/j.apmr.2015.12.029.OBJECTIVE: To examine the feasibility and efficacy of a home-based gait observation intervention for improving walking in Parkinson ...
Cronin-Golomb, Alice +5 more
core +1 more source
Differential diagnosis of parkinsonian degenerative disorders in combination manual measurements with automated volumetry of the brain [PDF]
Yiwei Zhang +8 more
openalex +1 more source

