Results 221 to 230 of about 450,934 (396)

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su   +13 more
wiley   +1 more source

Restless legs syndrome: abbreviated guidelines by the German sleep society and the German neurological society

open access: yesNeurological Research and Practice
Claudia Trenkwalder   +8 more
doaj   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li   +11 more
wiley   +1 more source

Incident parkinsonism in older adults without Parkinson disease

open access: yesNeurology, 2016
A. Buchman   +7 more
semanticscholar   +1 more source

Structural and Functional Versatility of the Amyloidogenic Non‐Amidated Variant of the Antimicrobial Peptide Citropin 1.3

open access: yesAdvanced Science, EarlyView.
Citropin 1.3 is an antimicrobial peptide derived from amphibians that forms amyloid structures. Here, the structural and functional properties of citropin 1.3 are characterized. Using high‐resolution imaging approaches, a variety of canonical and undescribed fibril morphologies are identified.
Fabio Strati   +8 more
wiley   +1 more source

Parkinsonism in Gerstmann-Sträussler-Scheinker disease: A case report. [PDF]

open access: yeseNeurologicalSci
Poveda S   +4 more
europepmc   +1 more source

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