Results 221 to 230 of about 109,533 (316)

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

, 1996
Asako Yoritaka, Nobutaka Hattori, Kôji Uchida, Masashi Tanaka, Earl R. Stadtman, Yuri Mizuno   +5 more
openalex   +2 more sources

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

Advanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang, Xing‐Hua Ren, Cheng‐Hong Zhang, Zhan‐You Wang   +3 more
wiley   +1 more source

Multiple System Atrophy Without Dysautonomia: An Autopsy-Confirmed Study. [PDF]

Neurology
Wilkens I, Bebermeier S, Heine J, Ruf VC, Compta Y, Molina Porcel L, Troakes C, Vamanu A, Downes S, Irwin DJ, Cohen J, Lee EB, Nilsson CF, Englund EM, Nemati M, Katzdobler S, Levin J, Bernhardt AM, Pantelyat A, Seemiller J, Berger S, Van Swieten JC, Dopper EGP, Rozemuller AJM, Kovacs GG, Bendahan N, Lang AE, Herms J, Höglinger GU, Hopfner F.   +29 more
europepmc   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Lymphomatosis cerebri presenting with rapidly progressive parkinsonism and Holmes tremor: a case report. [PDF]

BMC Neurol
Iguchi T, Furuya T, Koinuma T, Nakajima A, Fuse A, Eguchi H, Sugiyama Y, Shimo Y.   +7 more
europepmc   +1 more source

Better balance with somatosensory exercises : a Parkinson perspective

, 2018
Ingrid M. Claesson
openalex  

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Kufor-Rakeb Syndrome in a Guatemalan Patient With an <i>ATP13A2</i> Gene Pathogenic Variant: A Case Report. [PDF]

Case Rep Genet
Méndez-Veras R, Urbizo A, Cabrera J, Boburg S.   +3 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Remodeling of Perineuronal Nets in the Striato-Cortical Axis in L-DOPA-Induced Dyskinesia Rat Model. [PDF]

Int J Mol Sci
Bilbay NT, Tel BC, Akkus G, Cakir-Aktas C, Solakoglu T, Yalcin-Cakmakli G, Elibol B.   +6 more
europepmc   +1 more source