Results 231 to 240 of about 435,882 (385)

Restless legs syndrome: abbreviated guidelines by the German sleep society and the German neurological society

open access: yesNeurological Research and Practice
Claudia Trenkwalder   +8 more
doaj   +1 more source

The Role of HINT3 in Myocardial Ischemia‐Reperfusion Injury in Male Mice: Mechanisms Involving SDHA and its Acetylation

open access: yesAdvanced Science, EarlyView.
HINT3 expression declines after myocardial ischemia‐reperfusion injury. In male mice, loss of HINT3 worsens cardiac injury and mitochondrial dysfunction, while its overexpression is protective. HINT3 binds the mitochondrial enzyme succinate dehydrogenase (SDHA) and prevents its deacetylation by histone deacetylase 1 (HDAC1), reducing succinate ...
Jiabin Yu   +7 more
wiley   +1 more source

Community Disadvantage Is Associated With More Severe Motor Symptoms in Parkinson Disease. [PDF]

open access: yesNeurol Clin Pract
Hill EJ   +19 more
europepmc   +1 more source

Incident parkinsonism in older adults without Parkinson disease

open access: yesNeurology, 2016
A. Buchman   +7 more
semanticscholar   +1 more source

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

Parkinsonism: Onset, progression, and mortality

open access: yesNeurology, 2011
M. Hoehn, M. Yahr
semanticscholar   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

open access: yesAdvanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria   +5 more
wiley   +1 more source

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