Results 231 to 240 of about 151,540 (363)

Parkinsonism, Psychomotor Slowing, Negative and Depressive Symptoms in Schizophrenia Spectrum and Mood Disorders: Exploring Their Intricate Nexus Using a Network Analytic Approach. [PDF]

open access: yesSchizophr Bull
Fritze S   +15 more
europepmc   +1 more source

Control of Recurrent Tachycardia of Wolff-Parkinson-White Syndrome by Surgical Ligature of the A-V Bundle [PDF]

open access: bronze, 1968
Leonard S. Dreifus   +4 more
openalex   +1 more source

Micro‐Coil Neuromodulation at Single‐Cell and Circuit Levels for Inhibiting Natural Neuroactivity, Neutralizing Electric Neural Excitation, and Suppressing Seizures

open access: yesAdvanced Science, EarlyView.
Micromagnetic stimulation (µMS) offers a precise method for neural inhibition, complementing existing neuromodulation techniques. Using an implantable micro‐coil device, µMS selectively suppresses cortical activity with high spatial resolution. It effectively counteracts micro‐electrode stimulation and reduces seizure amplitude, highlighting its ...
Kayeon Kim   +11 more
wiley   +1 more source

Bayesian Self‐Optimization for Telescoped Continuous Flow Synthesis

open access: yesAngewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023
An autonomous continuous flow platform for the rapid development of multistep synthetic pathways is reported. New multipoint sampling and Bayesian optimization techniques were combined, enabling simultaneous identification of optimum reaction conditions within a pharmaceutical process. The short optimization times achieved are promising for development
Adam D. Clayton   +9 more
wiley   +1 more source

Restless legs syndrome: abbreviated guidelines by the German sleep society and the German neurological society

open access: yesNeurological Research and Practice
Claudia Trenkwalder   +8 more
doaj   +1 more source

Integrated management of atypical parkinsonism: a home-based patient-centered healthcare delivery based on telenursing-the IMPACT study protocol. [PDF]

open access: yesTher Adv Neurol Disord
Cilia R   +23 more
europepmc   +1 more source

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

open access: yesAdvanced Science, EarlyView.
Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin   +9 more
wiley   +1 more source

DiffMC‐Gen: A Dual Denoising Diffusion Model for Multi‐Conditional Molecular Generation

open access: yesAdvanced Science, EarlyView.
DiffMC‐Gen, a dual‐diffusion model for 2D and 3D molecular generation, simultaneously optimizes multiple key objectives across the drug design process, enabling the generation of novel, target‐specific small‐molecule ligands with high therapeutic potential.
Yuwei Yang   +7 more
wiley   +1 more source

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