Results 241 to 250 of about 109,533 (316)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Neurobrucellosis manifesting as secondary hemiparkinsonism in a veterinary technician: A case report and evidence-based review. [PDF]

IDCases
Sanchez JD, Figueroa PAS, Figueroa MPS, Reinthaller HAC.   +3 more
europepmc   +1 more source

CONSIDERAÇÕES SOBRE A ORIGEM E A PROGRESSÃO DA DOENÇA DE PARKINSON, CORRELACIONANDO COM A VAGOTOMIA E A ESTIMULAÇÃO CEREBRAL PROFUNDA

L.C. Pinheiro, Cibele Mariano Vaz de Macêdo   +1 more
openalex   +2 more sources

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Idiopathic Parkinson's Disease Unmasked by Valproate-Induced Parkinsonism in a Patient With Vestibular Migraine. [PDF]

Cureus
Kamogashira T.
europepmc   +1 more source

Skin‐Conformal Myography for Real‐Time Hand Tracking Using a Laser‐Induced Graphene Strain Sensor Array

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A skin‐conformal wearable device based on laser‐induced graphene is developed for continuous strain measurement across the circumference of the forearm for gesture recognition and hand‐tracking applications. Post material optimization, the strain sensor array is integrated with a wearable wireless readout circuit for real‐time control of a robotic arm,
Vinay Kammarchedu, Monther AlSiyabi, Aida Ebrahimi   +2 more
wiley   +1 more source

Tofacitinib Improves Motor Symptoms in Parkinsonism Associated with a Heterozygous NGLY1 Variant and Autoimmune Disease. [PDF]

Eur J Case Rep Intern Med
Reina-Llompart N, Serrano-López S, Torres-Iglesias G, Álvarez-Troncoso J.   +3 more
europepmc   +1 more source

Neuronal-specific antibody in patients with multiple system atrophy and progressive supranuclear palsy. [PDF]

J Formos Med Assoc
Fang MS, Tsai MC, Arlt FA, Li CH, Fan SP, Chen PS, Chang YY, Lan MY, Wu YR, Hsiao IT, Chiang HL, Chen CY, Lee TL, Chang HC, Hsu JL, Lu CS, McKeon A, Lin CH, Taiwan PSP/CBS consortium.   +18 more
europepmc   +1 more source

Quantitative Assessment of Upper Limb Ataxia Using a Virtual Reality-Based Evaluation System. [PDF]

Ann Clin Transl Neurol
Sato M, Abe T, Aoki S, Tsukagoshi S, Yuminaka Y, Ikeda Y.   +5 more
europepmc   +1 more source

Os caminhos percorridos para o tratamento do paciente portador da doença de Parkinson e seus familiares

Amélia Aparecida Alarcon Faria, Alan Kardec dos Santos Sousa, Walquíria Lene dos Santos, Elias Rocha de Azevedo Filho, Gilney Guerra de Medeiros, Maria Liz Cunha de Oliveira, Filipa Ferreira, Celiandro José Scandolara Mazarro   +7 more
openalex   +2 more sources