Results 161 to 170 of about 127,921 (347)

Symptoms and Possible Causes Cures for Parkinsons Disease

, 2021
Parkinson’s disease is the world’s second most common neurodegenerative disorder, afflicting nearly 10 million people worldwide.1 While it is a fairly common disease, its exact causes are unknown and there is no known cure.
McHenry, Michael
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Pisa syndrome in Parkinson's disease: diagnostic and management challenges

, 2016
Vladimir Miletić
openalex   +2 more sources

Quantitative Proteomics Identifies Surfactant-Resistant α-Synuclein in Cerebral Cortex of Parkinsonism-Dementia Complex of Guam but Not Alzheimer's Disease or Progressive Supranuclear Palsy [PDF]

, 2007
Wan Yang, Randall L. Woltjer, Izabela Sokal, Catherine Pan, Yan Wang, Mary Brodey, Elaine R. Peskind, James B. Leverenz, Jing Zhang, Daniel P. Perl, Douglas Galasko, Thomas J. Montine   +11 more
openalex   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Reduction of L-DOPA-induced dyskinesia in animal models of Parkinson disease [PDF]

, 2009

openalex   +1 more source

Dataset and figures related to "Reduction of a-synuclein aggregates by PIKfyve inhibition via TFEB-mediated lysosomal biogenesis in a Parkinson disease model" preprint (Lucas Del-Pozo & Uras et al., 2023)

, 2023
Lucas-Del-Pozo, Sara, Uras, Giuseppe, Fierli, Federico, Lentini, Veronica, Koletsi, Sofia, Chau, Kai-Yin, Hughes, Derralynn, Schapira, Anthony   +7 more
openalex   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

Advanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul, Aiyarin Kittilukkana, Luis C. C. Huarte, Hiram Castillo‐Michel, Murielle Salome, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Monica Fernandez‐Monreal, Daniel Choquet, Richard Ortega, Asuncion Carmona   +12 more
wiley   +1 more source

Vocal Sound Pressure Level and Self-Perception of Speech and Voice in Men and Women With Idiopathic Parkinson Disease

, 1997
Cynthia Fox, Lorraine O. Ramig
openalex   +1 more source

Impact of deep brain stimulation on gait in Parkinson disease: A kinematic study [PDF]

, 2023
Richa Tripathi, J. Lucas McKay, Stewart A. Factor, Christine D. Esper, Douglas Bernhard, Paola Testini, Svjetlana Miocinovic   +6 more
openalex   +1 more source