Results 271 to 280 of about 127,921 (347)

Machine learning-based optimization of dual subthalamic nucleus and substantia nigra targeting in deep brain stimulation. [PDF]

NPJ Parkinsons Dis
Leavitt D, Negahbani F, Gharabaghi A.
europepmc   +1 more source

Additional file 1 of Loss of Parkinson Disease Protein 7 (PARK7) upregulates ROS and cell migration and is associated with recurrent pregnancy loss

Zhiqi Yang, Emily Hellwich, Nisha Mohd Rafiq, Alvin Joselin, Doo Soon Im, Gaurav Kaushik, Yogesh Singh, Biserka Mulac-Jericevic, Huanhuan Jiang, Irene González-Menéndez, Leticia Quintanilla‐Martinez, Sara Y. Brucker, Tilman E. Schäffer, Madhuri S. Salker   +13 more
openalex   +1 more source

Parkinsonism as an initial presentation of Creutzfeldt‐Jakob disease: A case report and review of literature [PDF]

S. Bahrami, Asal Sadat Karimi, Sepehr Khosravi, Mostafa Almasi‐Dooghaee   +3 more
openalex   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Parkinson's Disease

Harvard Data Science Review, 2018
Flavio Fröhlich
doaj   +1 more source

Sex differences in the severity of non-motor symptoms in Parkinson's disease: a systematic review and meta-analysis. [PDF]

NPJ Parkinsons Dis
Cicero CE, Terravecchia C, Pettinato LL, Tabbì S, Donzuso G, Contrafatto D, Mostile G, Zappia M, Nicoletti A.   +8 more
europepmc   +1 more source

Citrus aurantium honey‐mediated gut homeostasis and anti‐inflammation via Thorl/Nprl2‐TORC1 signaling: Network pharmacology and Drosophila validation

Animal Models and Experimental Medicine, EarlyView.
The study employed a four‐tiered strategy: (1) UHPLC‐FTMS profiling of Citrus aurantium honey to characterize its chemical composition; (2) network pharmacology analysis integrating target prediction, protein–protein interaction networks, and KEGG pathway enrichment to identify the Thor1/Nprl2‐TORC1 axis as a key mechanistic pathway; (3) in vitro ...
Wenqi Wan, Ruiguang Huang, Shuqiong Cao, Luxia Pan, Wenkai Zhang, Wujun Jiang, Zhiyong Liu   +6 more
wiley   +1 more source

Author Correction: Proceedings of the world summit on parkinson's disease. [PDF]

NPJ Parkinsons Dis
Mantri S, Ghilardi MF, Lessard N, Norcini M, Di Rocco A, Wallock K, Lehr J, Okun MS, World Summit Steering Committee.   +8 more
europepmc   +1 more source

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Striatal hyperechogenicity as an ultrasound imaging marker for prodromal X-linked dystonia-parkinsonism. [PDF]

NPJ Parkinsons Dis
Pauly MG, Diesta CCE, Cataniag P, Borsche M, Hanssen H, Oropilla JQL, Walter U, Dressler D, Algodon SM, Westenberger A, Klein C, Brüggemann N.   +11 more
europepmc   +1 more source