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Parkinson's disease [PDF]

open access: yesHuman Molecular Genetics, 2007
Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by a profound and selective loss of nigrostriatal dopaminergic neurons. Clinical manifestations of this complex disease include motor impairments involving resting tremor, bradykinesia, postural instability, gait difficulty and rigidity.
Bobby, Thomas, M Flint, Beal
openaire   +5 more sources

Moving Children and Adolescents

open access: yesDeutsche Zeitschrift für Sportmedizin, 2019
Cerebral infarcts and haemorrhages, dementia, Parkinsons disease, sarcopenia, falls,and insomnia have in common that they frequently occur in higher ages, may considerably impair quality of life and cannot be primarily prevented by medication.
Reimers CD
doaj   +1 more source

COGNITIVE AND AFFECTIVE DISORDERS AT EARLY STAGES OF PARKINSON’S DISEASE

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Background: Non-motor signs, including affective and cognitive ones, are important initial manifestations of Parkinsons disease, along with motor dysfunction. Some of them manifest even before motor disorders and affect patients’ quality of life. Aim: To
R. R. Bogdanov   +2 more
doaj   +1 more source

A REVIEW ON IMPORTANCE OF ARTIFICIAL INTELLIGENCE IN PARKINSONS DISEASE & ITS FUTURE OUTCOMES FOR PARKINSONS DISEASE

open access: yes, 2021
Over the centurys, increasingly sophisticated tools have been developed to serve humanity. In many ways, digital computers are just another tool. You can perform the same number and symbol operations as ordinary people, but it is faster and more reliable.
Patel Minesh
core   +1 more source

Parkinson’s disease over the last 20 years – new concepts and developments

open access: yesAdvances in Clinical Neuroscience & Rehabilitation, 2020
Much has changed in our understanding and approach to Parkinson’s Disease (PD). This in part is because of new scientific methods such as the discovery of how to make induced pluripotent stem cells (iPSCs); the development of improved gene editing ...
Barker, Roger
doaj   +1 more source

Disease modifying treatments for Parkinson’s disease – an update

open access: yesAdvances in Clinical Neuroscience & Rehabilitation, 2021
An improved understanding of the pathological processes leading to neurodegeneration in Parkinson’s disease (PD) is leading to the development of a number of disease modifying agents. These include both novel and repurposed drugs.
Vijay Chandran, Donald G Grosset
doaj   +1 more source

Deep Brain Stimulation of bilateral Subthalamic nucleus (STN) following pallidotomy with Parkinsons crisis: A case report

open access: yesNepal Journal of Neuroscience, 2018
We present a case of 57 years old patient with Idiopathic Parkinsons disease(PD) who had right sided Globus PallidusInternus (GPi) lesioning or pallidotomy as surgical treatment modality of PD.
Resha Shrestha   +4 more
doaj   +1 more source

Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson’s Disease

open access: yesParkinson's Disease, 2020
Purpose. Autonomic dysfunction is a common nonmotor feature and early manifestation of Parkinsons disease (PD). Autonomic dysfunction in PD is associated with a worse prognosis.
Daniel Martinez-Ramirez   +8 more
doaj   +1 more source

Prosody and levodopa in Parkinsons disease

open access: yesArquivos de Neuro-Psiquiatria, 2013
Objective Research is scarce regarding the use of prosodic parameters in the expression of attitudes in Parkinson’s disease (PD). The purpose of this study was to evaluate the parameters used in prosodic expression of attitudes in individuals with ...
Luciana Lemos de Azevedo   +3 more
doaj   +1 more source

Test-retest reliability of physical activity questionnaires in Parkinsons disease

open access: yes, 2021
Background People with Parkinsons disease are less physically active than controls. It is important to promote physical activity, which can be assessed using different methods.
Ånfors, Samuel   +9 more
core   +1 more source

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