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Parkinson disease (PD) is a neurodegenerative movement disorder that is increasing in prevalence especially as the population continues to age. This article provides an overview of the clinical presentation and evaluation for PD, genetic and environmental risk factors, and current treatments.New treatments for motor symptoms of PD (eg, motor ...
Ashley, Rawls, Michael S, Okun
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Parkinson disease (PD) is a neurodegenerative movement disorder that is increasing in prevalence especially as the population continues to age. This article provides an overview of the clinical presentation and evaluation for PD, genetic and environmental risk factors, and current treatments.New treatments for motor symptoms of PD (eg, motor ...
Ashley, Rawls, Michael S, Okun
openaire +4 more sources
2013
There have been a large number of basic research studies of noninvasive brain stimulation in Parkinson's disease. Initial work focused on measuring: (1) the excitability of corticospinal output with threshold and input-output measures, and (2) the effectiveness of intracortical γ-aminobutyric acid (GABA)ergic inhibitory systems using short-interval ...
John C, Rothwell, Mark J, Edwards
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There have been a large number of basic research studies of noninvasive brain stimulation in Parkinson's disease. Initial work focused on measuring: (1) the excitability of corticospinal output with threshold and input-output measures, and (2) the effectiveness of intracortical γ-aminobutyric acid (GABA)ergic inhibitory systems using short-interval ...
John C, Rothwell, Mark J, Edwards
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Medical Clinics of North America, 2019
The diagnosis of Parkinson disease (PD) is based on the presence of bradykinesia and either resting tremor or rigidity and there should be no features from the history or examination to suggest an alternative cause of parkinsonism. In addition to the motor manifestations of PD, there is a long list of nonmotor symptoms, several of which occur before ...
Stephen G, Reich, Joseph M, Savitt
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The diagnosis of Parkinson disease (PD) is based on the presence of bradykinesia and either resting tremor or rigidity and there should be no features from the history or examination to suggest an alternative cause of parkinsonism. In addition to the motor manifestations of PD, there is a long list of nonmotor symptoms, several of which occur before ...
Stephen G, Reich, Joseph M, Savitt
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Medical Journal of Australia, 1993
The prevalence of Parkinson's disease rises with age. The clinical features can be the typical ones or those associated with the "late-onset" type, with more gait and balance problems and a mild progressive dementia. Other disorders, such as stroke and essential tremor, may be mistaken for Parkinson's disease, or multiple conditions may be present ...
H M, Creasey, G A, Broe
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The prevalence of Parkinson's disease rises with age. The clinical features can be the typical ones or those associated with the "late-onset" type, with more gait and balance problems and a mild progressive dementia. Other disorders, such as stroke and essential tremor, may be mistaken for Parkinson's disease, or multiple conditions may be present ...
H M, Creasey, G A, Broe
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The Lancet, 2009
Parkinson's disease is a common progressive bradykinetic disorder that can be accurately diagnosed. It is characterised by the presence of severe pars-compacta nigral-cell loss, and accumulation of aggregated alpha-synuclein in specific brain stem, spinal cord, and cortical regions. The main known risk factor is age.
Andrew J, Lees +2 more
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Parkinson's disease is a common progressive bradykinetic disorder that can be accurately diagnosed. It is characterised by the presence of severe pars-compacta nigral-cell loss, and accumulation of aggregated alpha-synuclein in specific brain stem, spinal cord, and cortical regions. The main known risk factor is age.
Andrew J, Lees +2 more
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Parkinson's disease, Parkinsonism and aging
Archives of Gerontology and Geriatrics, 2002NICITA MAURO, Vittorio +5 more
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Annals of Internal Medicine, 2018
Parkinson disease is a common neurodegenerative disorder that causes progressive motor and nonmotor disability. It is diagnosed clinically and requires a detailed history and neurologic examination to exclude alternative diagnoses. Although disease-modifying therapies do not exist for Parkinson disease, effective symptomatic therapies, including ...
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Parkinson disease is a common neurodegenerative disorder that causes progressive motor and nonmotor disability. It is diagnosed clinically and requires a detailed history and neurologic examination to exclude alternative diagnoses. Although disease-modifying therapies do not exist for Parkinson disease, effective symptomatic therapies, including ...
openaire +2 more sources
Australian family physician, 1971
The classical clinical picture of Parkinson's disease is all too frequently encountered in the elderly patient. The modern classification of causes of Parkinson's disease lists 'idiopathic', and 'post-encephalitic forms', the latter being uncommon in this community.
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The classical clinical picture of Parkinson's disease is all too frequently encountered in the elderly patient. The modern classification of causes of Parkinson's disease lists 'idiopathic', and 'post-encephalitic forms', the latter being uncommon in this community.
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Stalevo®: A pioneering treatment for OFF periods in Parkinsons disease
European Journal of Neurology, 2023Peter Jenner
exaly