Results 91 to 100 of about 891,705 (311)
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Public administration of safety of navigation: multi-level challenges and answers
The article addresses the advantages and shortcomings of multi-level system of ensuring safety of navigation. The principle of the navigation safety is considered as fundamental determinant of changes in maritime laws and regulations at the international,
Tetiana Plachkova, Oleksandr Avdieiev
doaj +1 more source
Statutes and Ordinances and Acts of the Parliament of Ireland, King John to Henry V [PDF]
Henry Berry
openalex +1 more source
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
wiley +1 more source
The Influence of Parliament upon the Foreign Policy of the Gladstone Government 1868–74 [PDF]
Sheila Lambert
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
HUMAN SECURITY AGENDA- IDEOLOGICAL BASIS AND DEVELOPMENT IN THE CONTEXT OF CANADIAN FOREIGN POLICY
In accordance with the bases of liberal internationalism, the political moral community can be extended beyond the boundaries of the national state. The presence of the moral dimension is inherent to foreign policy, including a foreign political agenda ...
Dragan Božović
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Staging European Union Democracy: Discussion Paper Prepared for the 'Round Table on a Sustainable Project for Europe'. EPIN Working Paper No. 10, December 2003 [PDF]
Much of the malaise surrounding EU democracy can be accounted for by the fact that there is no effective staging of political debate between the European Parliament and EU executive power.
Crum, Ben.
core