Results 61 to 70 of about 913,370 (314)
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Geleitwort zur Konferenz „Vielfalt und Demokratie – Identitätssuche in unübersichtlichen Zeiten“
Prof. Dr. Dr. h.c. mult. Rita Süßmuth, Präsidentin des Deutschen Bundestages a.D.
Rita Süßmuth
doaj +1 more source
Designing an institutional network for improving farm animal welfare in the EU [PDF]
Improvements in the welfare of farmed animals in the EU have been achieved by legislation, increased welfare capacity in the food chain, greater public awareness, welfare measurement tools and dissemination of best practice.
Aguilar+18 more
core +1 more source
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
wiley +1 more source
Conflict without an Apparent Cause
A game-theoretic model of repeated interaction between two potential adversaries is analyzed to illustrate how conflict could possibly arise from rational decision-makers endogenously processing information, without any exogenous changes to the ...
Timothy Mathews, Aniruddha Bagchi
doaj +1 more source
The evaluative role of legislatures in creating a responsive executive
The ability of legislatures to play a more effective oversight role is intricately linked to its ability to properly conceptualise and institutionalise its monitoring and evaluation (ME) function.
Reitumetse Zantsi
doaj +1 more source
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source