Results 61 to 70 of about 936,030 (313)
Ekonomika, 2020 The article aims at ascertaining the relationship between indicators affecting the green economic growth of the Eurozone countries. Despite extensive research, scientists have not yet found a clear answer as to whether economic growth and climate change ...
Violeta Klyviene, Angele Kedaitiene
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Staging European Union Democracy: Discussion Paper Prepared for the 'Round Table on a Sustainable Project for Europe'. EPIN Working Paper No. 10, December 2003 [PDF]
, 2003 Much of the malaise surrounding EU democracy can be accounted for by the fact that there is no effective staging of political debate between the European Parliament and EU executive power.
Crum, Ben.
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Analysis of national health accounts in Iran (2002–2020) [PDF]
PayeshObjective (s): Comprehensive data on health expenditures is crucial not only for effective policymaking but also for achieving universal health coverage and health-related sustainable development goals.
Abdoreza Mousavi +3 more
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Příspěvek k jubileu Bedřicha Moldana
EnvigogikaJen pokud dokážeme pečovat o naši planetu, vytvoříme stabilní základ pro růst a rozvoj společnosti. Profesor Bedřich Moldan byl jedním z těch, kdo tuto skutečnost dokázali srozumitelně a přesvědčivě přinášet do veřejné debaty i politického rozhodování.
Luděk Niedermayer
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FINANCING OF GROWTH IN AGRICULTURAL COOPERATIVES [PDF]
Sources and uses of funds in agricultural cooperatives are examined and compared to the aggregate of nonfinancial corporations for the period 1973-1987. Cooperatives are observed to finance nearly half their growth with equity.
Lerman, Zvi, Parliament, Claudia
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source