Results 151 to 160 of about 8,082 (209)

Repair of Congenital Cardiac Disease Requiring Bypass for a Pediatric Patient With Paroxysmal Nocturnal Hemoglobinuria. [PDF]

JACC Case Rep
Blumenthal M, Chandra A, Robinette M, Hibino N, Nelson-McMillan K, Kaviany S, Ganigara M, Pophal S.   +7 more
europepmc   +1 more source

Characterization of Breakthrough Hemolysis in Patients With Paroxysmal Nocturnal Hemoglobinuria: An International Multicenter Experience. [PDF]

Am J Hematol
Fattizzo B, Pedone GL, Metafuni E, Beggiato E, Giai V, Natalie Oliva E, Ricchiuti A, Bortolotti M, Raso S, Carlino D, Memoli M, Vecchi S, Vidler J, Gogoi S, Goel S, Corby A, Trikha R, Balakrishnan S, Passamonti F, Paola Iori A, Sica S, Gandhi S, Barcellini W, Kulasekararaj A.   +23 more
europepmc   +1 more source

Treatment burden in patients with paroxysmal nocturnal hemoglobinuria: an in-depth interview survey. [PDF]

Ann Hematol
Ueda Y, Obara N, Ueno S, Sakurai M, Hosokawa K, Murata T, Fukuoka Y, Hayama N, Yamashita M, Ogawa Y, Usuki K, Ikezoe T, Kawaguchi T, Hosen N, Kanakura Y, Gotoh A, Nishimura JI.   +16 more
europepmc   +1 more source

Paroxysmal Nocturnal Hemoglobinuria: Unraveling Its Molecular Pathogenesis and Advancing Targeted Therapeutic Strategies. [PDF]

Diseases
Apostolidou E, Georgoulis V, Leonardos D, Kapsali E, Hatzimichael E.   +4 more
europepmc   +1 more source

Paroxysmal Nocturnal Hemoglobinuria in Children

Pediatric Drugs, 2007
Paroxysmal nocturnal hemoglobinuria (PNH), an acquired hematologic disorder characterized by intravascular hemolysis, nocturnal hemoglobinuria, thrombotic events, serious infections, and bone marrow failure, is very rare in children. PNH is caused by a somatic mutation of the phosphatidylinositol glycan (GPI) complementation class A (PIGA) gene ...
Heuvel-Eibrink, M.M. (Marry) van den, Van den Heuvel - Eibrink, Marry   +1 more
openaire   +4 more sources

Pregnancy and paroxysmal nocturnal hemoglobinuria

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1994
A patient is described who developed symptoms of paroxysmal nocturnal hemoglobinuria (PNH) in her first pregnancy. This was uneventful except for a spontaneous preterm delivery. The second pregnancy was complicated by severe anemia and a hemolytic crisis with Budd-Chiari syndrome at 31 weeks' amenorrhoea.
Bais, J., Pel, M., von dem Borne, A., van der Lelie, H.   +3 more
openaire   +4 more sources

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Pegcetacoplan for paroxysmal nocturnal hemoglobinuria

Blood, 2022
AbstractApproximately a third of patients with paroxysmal nocturnal hemoglobinuria (PNH) remain transfusion dependent or have symptomatic anemia despite treatment with a C5 inhibitor. Pegcetacoplan inhibits complement proximally at the level of C3 and is highly effective in treating persistent anemia resulting from C3-mediated extravascular hemolysis ...
Gloria F. Gerber, Robert A. Brodsky
openaire   +2 more sources