Results 191 to 200 of about 32,646 (215)
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Current Advances in PARP1‐Targeted Theranostics
Journal of Labelled Compounds and RadiopharmaceuticalsABSTRACTPoly (ADP‐ribose) polymerase 1 (PARP1) plays critical roles in DNA repair, chromatin regulation, and cellular equilibrium, positioning it as a pivotal target for therapeutic interventions in cancer and central nervous system (CNS) disorders.
Jie Tong +5 more
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PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2012
Qing-Wei HUO, Dong-Feng LI, Cheng LONG
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Qing-Wei HUO, Dong-Feng LI, Cheng LONG
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The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer
Molecular Cell, 2021Karoline Schnizer-Luger +2 more
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Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in Drosophila
Proceedings of the National Academy of Sciences of the United States of America, 2023Qiongyue Zhang +2 more
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An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation
Cell, 2020Orsolya Leidecker +2 more
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Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner
Proceedings of the National Academy of Sciences of the United States of America, 2023Brian Lee +2 more
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